Constance Baaten

Post doc

Dr. Constance Baaten is a postdoctoral researcher in the thrombosis and hemostasis field. She obtained her bachelor’s and master’s degrees in Molecular Life Sciences at Maastricht University. Subsequently, she started her PhD research at the department of Biochemistry at CARIM under the supervision of Prof. Johan Heemskerk and Dr. Paola van der Meijden, focusing on the acquired impairment and recovery of platelet function. Upon obtaining her PhD degree in 2018, Constance joined the group of Dr. Heidi Noels at the Institute for Molecular Cardiovascular Research (IMCAR) at the University Hospital Aachen with an Alexander von Humboldt fellowship for postdoctoral researchers. With this fellowship she was able to investigate platelet function in the context of chronic kidney disease. In 2020, she was awarded the prestigious Dekker grant for postdoctoral researchers by the Dutch Heart Foundation that allowed her to join the group of Prof. Hugo ten Cate at the department of Biochemistry to study platelet-platelet interactions while maintaining her postdoc position at the IMCAR institute.

Currently, Constance works as a researcher within the group of Prof. Henri Spronk at the Department of Biochemistry at CARIM and the group of Dr. Heidi Noels within the IMCAR institute. She continues to investigate platelet function in different pathophysiological conditions and is involved in the recently initiated study on thrombo-inflammation in post-COVID. Over the years, she has gained expertise in studying interactions between vascular cells (endothelial and vascular smooth muscle cells), immune cells (neutrophils, monocytes) and platelets.

Department of Biochemistry
Universiteitssingel 50, 6229 ER Maastricht
Room number: H1.314
T: +31(0)88 388 7444

2025
- Baaten, C. C. F. M. J., Wollenhaupt, J., Henning, T. M., Vondenhoff, S., Schröer, J. R., Stamellou, E., Saritas, T., Kurt, B., Boger, L., Antwerpen, A., Hermann, J., Nagy, M., Sternkopf, M., Buhl, E. M., Raffetseder, U., van der Meijden, P. E. J., Kuijpers, M. J. E., Spronk, H. M. H., Schunk, S. J., ... Noels, H. (2025). Impaired Secondary Platelet Response in Chronic Kidney Disease as a Consequence of Prior Platelet Activation. JACC: Basic to Translational Science, 10(9), Article 101355. https://doi.org/10.1016/j.jacbts.2025.101355
- van Dievoet, M.-A., Baaten, C. C., Nagy, M., David, C., Brusa, D., Dahlqvist, G., Coubeau, L., De Bruyne, R., Jannone, G., Scheers, I., Hermans, C., Tambucci, R., Pirotte, T., de Magnee, C., Sokal, E., Horman, S., Douxfils, J., Heemskerk, J. W., Lisman, T., & Stephenne, X. (2025). Primary hemostasis in children with cirrhosis prior to liver transplantation: key roles of liver disease severity, von Willebrand factor, and platelet count. Journal of Thrombosis and Haemostasis, 23(7), 2297-2313. https://doi.org/10.1016/j.jtha.2025.04.010
- Lauxen, J. S., Vondenhoff, S., Junho, C. V. C., Martin, P., Fleig, S., Schuett, K., Schulze-Spaete, U., Soehnlein, O., Prates-Roma, L., Doering, Y., Baaten, C. C. F. M. J., & Noels, H. (2025). Neutrophil Function in Patients With Chronic Kidney Disease: A Systematic Review and Meta-Analysis. Acta Physiologica, 241(6), Article e70057. https://doi.org/10.1111/apha.70057
- Nagy, M., Bender, M., Poulter, N. S., Pike, J. A., Sickmann, A., Vondenhoff, S., Bielicka, N., van Zandvoort, M. A. M. J., Koenen, R. R., ten Cate, H., Stéphenne, X., Heemskerk, J. W. M., & Baaten, C. C. F. M. J. (2025). Formation of tight junction-like structures of zonula occludens 2 in platelet–platelet interaction. Research and practice in thrombosis and haemostasis, 9(3), Article 102845. https://doi.org/10.1016/j.rpth.2025.102845
2024
- Baaten, C. C. F. M. J., Nagy, M., Spronk, H. M. H., Ten Cate, H., & Kietselaer, B. L. J. H. (2024). NETosis in Cardiovascular Disease: An Opportunity for Personalized Antithrombotic Treatments?Arteriosclerosis Thrombosis and Vascular Biology, 44(12), 2366-2370. https://doi.org/10.1161/ATVBAHA.124.320150
- Baaten, C. C. F. M. J., Nagy, M., Bergmeier, W., Spronk, H. M. H., & van der Meijden, P. E. J. (2024). Platelet biology and function: plaque erosion vs. rupture. European Heart Journal, 45(1), 18-31. https://doi.org/10.1093/eurheartj/ehad720
2023
- Baaten, C. C. F. M. J., Vondenhoff, S., Jankowski, J., & Noels, H. (2023). Thrombozytenstörungen bei Urämie: Mediator von Herz- und Gefäßschäden. Die Nephrologie, 18(6), 346–354. https://doi.org/10.1007/s11560-023-00682-2
- Akbalut, C., Arisz, R., Baaten, C., Baildildinova, G., Barakzie, A., Bauersachs, R., Ten Berg, J. M., van den Broek, W., de Boer, H. C., Broker, V., Buka, R., Ten Cate, H., Cate, A. T., De Luca, C., De Simone, I., Dignat-George, F., Freson, K., Gazzaniga, G., van Gorp, E., ... van Zonneveld, A.-J. (2023). Blood coagulation and beyond: Position paper from the Fourth Maastricht Consensus Conference on Thrombosis. Thrombosis and Haemostasis, 123(8), 808-839. https://doi.org/10.1055/a-2052-9175
- De Simone, I., Baaten, C. C. F. M. J., Gibbins, J. M., Ten Cate, H., Heemskerk, J. W. M., Jones, C. I., & van der Meijden, P. E. J. (2023). Repeated platelet activation and the potential of previously activated platelets to contribute to thrombus formation. Journal of Thrombosis and Haemostasis, 21(5), 1289-1306. https://doi.org/10.1016/j.jtha.2023.01.006

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Constance Baaten

Post doc