Job Verdonschot

Assistant Professor

Dr. Job Verdonschot is a resident at the Clinical Genetics department of the Maastricht UMC+ and an assistant professor at the Cardiology department within CARIM of the Maastricht University.

He finished both a master in biomedical sciences and medicine (cum laude) at the university of Maastricht, with a differentiation in cardiogenetics. In 2016 he received a Kootstra Talent Fellowship to start a PhD investigating the impact of genetic mutations on the clinical course of patients with dilated cardiomyopathy. His PhD thesis received three prizes for best thesis of 2021: by the Dutch association of clinical genetics (VKGN), the Durch association of cardiology (NVVC) and the CARIM research school of the university of Maastricht. In 2021 he started his clinical training to become a clinical geneticist in the Maastricht UMC+ with a differentiation in cardiology and cardiogenetics, which he will finish in 2025, continuing his career as clinical geneticist at the department.

In 2022 he received the prestigious Dekker grant (Clinical Scientist) from the Dutch Heart Foundation to start his research group investigating the impact of genetic mutations for asymptomatic family members. In 2023 and 2024 he also received the Academic Funds and a Veni grant of the NWO to further expand his research line focusing on early detection, improving risk stratification and early treatment, and reproductive options for patients and their family members with a genetic form of dilated cardiomyopathy.

He contributes to multiple national and international committees (for example, he is chair of the national Study Group on family care for cardiomyopathy patients of the National Heart Institute, and leads the writing of international consensus documents on family care and reproductive options from the European Society of Cardiology). He has a strong focus on interdisciplinary collaborations to achieve innovation in health care, depicted by collaboration with the Dutch Forensic Institute (NOFA study funded by ZonMW), the technical University of Eindhoven (as part of the Veni project) and hematology (focusing on clonal hematopoiesis as part of his ERA4HEALTH grant). His goal is to translate research innovations to clinical implementation to improve the care for patients and family members with genetic forms of dilated cardiomyopathy.

Department of Cardiology 
Universiteitssingel 50, 6229 ER, Maastricht
P.O. Box 616, 6200 MD Maastricht

Room number: 3.K1.031
T: +31 (0) 43 387 10 98

  • 2026
    • Peretto, G., Merlo, M., Ambrosi, A., Bacigalupi, E., Villatore, A., Molinari, L., Anguera, I., Claver, E., Dal Ferro, M., Suwalski, P., Spartalis, M., Verdonschot, J., Ciabatti, M., Martini, N., Zampieri, M., Paldino, A., Valeri, Y., Radesich, C., Lazzeroni, D., ... Sinagra, G. (2026). Major arrhythmias in non-dilated left ventricular cardiomyopathy: a novel prediction score. European Heart Journal, 47(1), 94-106. Article ehaf477. https://doi.org/10.1093/eurheartj/ehaf477
    • Venner, M. F. G. H. M., Verdonschot, J. A. J., & Knackstedt, C. (2026). Letter to the editor: Diastolic dysfunction as predictive parameter for the development of post-TIPS cardiac decompensation. International Journal of Cardiology, 442, Article 133886. https://doi.org/10.1016/j.ijcard.2025.133886
  • 2025
    • Faassen, I. M. E., Heijligers, M., Weijermans, N. H. N., van Buul-van Zwet, M. L., Zietse, C. S., Zamani Esteki, M., Paulussen, A. D. C., & Verdonschot, J. A. J. (2025). Preimplantation genetic testing for cardiomyopathies: a case series illustrating the clinical and technological perspective. European Heart Journal - Case Reports, 9(12), Article ytaf630. https://doi.org/10.1093/ehjcr/ytaf630
    • Stroeks, S. L. V. M., Wang, P., Merlo, M., Muller, S., Paldino, A., Mora-Ayestaran, N., Jason, M., Ferro, M. D., Loca, C. P., Dominguez, F., Gonzalez-Lopez, E., van den Wijngaard, A., Venner, M. F. G. H. M., Sikking, M., Minten, M., Nihant, B., Beelen, N., Graw, S., Medo, K., ... Verdonschot, J. A. J. (2025). Impact of genotype-phenotype associations on prognosis in dilated cardiomyopathy. European journal of heart failure, 27(12), 3205-3218. https://doi.org/10.1002/ejhf.70040
    • Verdonschot, J. A. J., Kaski, J. P., Asselbergs, F. W., Behr, E. R., Charron, P., Dawson, D., Haugaa, K. H., Kuchynka, P., Lopes, L. R., Mazzanti, A., Monserrat, L., Pantazis, A., Prasad, S. K., Schunkert, H., Seferovic, P. M., Sheppard, M. N., Sinagra, G., van Tintelen, J. P., Tome Esteban, M. T., ... Garcia-Pavia, P. (2025). Clinical care of family members of patients with dilated cardiomyopathy: A clinical consensus statement of the Heart Failure Association of the European Society of Cardiology, the European Society of Cardiology Working Group on Myocardial & Pericardial Diseases, and the European Society of Cardiology Council on Cardiovascular Genomics. European Heart Journal, 46(43), 4569-4582. Article ehaf571. https://doi.org/10.1093/eurheartj/ehaf571
    • Venner, M. F. G. H. M., Heymans, A. B. M., Beelen, N. J., Stroeks, S. L. V. M., Faassen, I. M. E., Sikking, M. A., Henkens, M. T. H. M., Van Der Crabben, S. N., Raafs, A. G., Heymans, S. R. B., & Verdonschot, J. A. J. (2025). Predictive value of ambulatory ECG monitoring for malignant arrhythmic events in genetic dilated cardiomyopathy. EP Europace, 27(11), Article euaf279. https://doi.org/10.1093/europace/euaf279
    • Stroeks, S. L. V. M., Merlo, M., Mora-Ayestaran, N., Jason, M., Tayal, U., Wang, P., Cannatà, A., Sikking, M. A., Dal Ferro, M., Peiro, B., Willemars, M., Hellebrekers, D. M. E. I., van Leeuwen, R. E. W., Setti, M., Gonzalez-Lopez, E., Krapels, I. P. C., Pio Loco Detto Gava, C., van den Wijngaard, A., Henkens, M. T. H. M., ... Verdonschot, J. A. J. (2025). Sex Differences in Prognosis of Patients With Genetic Dilated Cardiomyopathy. Circulation-Heart Failure, 18(11), e012592. Article 012592. https://doi.org/10.1161/CIRCHEARTFAILURE.124.012592
    • Gigli, M., Verdonschot, J. A. J., Garcia-Pavia, P., Stolfo, D., Monserrat, L., Prasad, S., Mazzanti, A., Asselbergs, F. W., Bauce, B., Charron, P., Dawson, D., Halliday, B. P., Mestroni, L., Seferovic, P., Tayal, U., Esteban, M. T. T., Van Tintelen, P., Heymans, S., Pantazis, A., ... Sinagra, G. (2025). Future development of arrhythmogenic risk scores in patients with heart failure and inherited dilated cardiomyopathy. A scientific statement of the Heart Failure Association of the ESC. European journal of heart failure, 27(11), 2229-2243. https://doi.org/10.1002/ejhf.70042
    • Setti, M., Iseppi, M., Verdonschot, J. A. J., Rizzi, J. G., Paldino, A., Gava, C. P. L. D., Barbati, G., Dal Ferro, M., Venner, M. F. G. H. M., Raafs, A. G., Gigli, M., Stolfo, D., De Luca, A., De Angelis, G., Capovilla, T. M., Graw, S., Ribichini, F. L., Taylor, M., Mestroni, L., ... Merlo, M. (2025). Integrated role of cardiac magnetic resonance and genetics in predicting left ventricular reverse remodelling in dilated and non-dilated cardiomyopathy. European journal of heart failure, 27(11), 2571-2581. Article 3671. https://doi.org/10.1002/ejhf.3671
    • Heymans, A. B. M., Bianchi, L., Volders, P. G. A., van der Crabben, S. N., & Verdonschot, J. A. J. (2025). SCN5A Cardiomyopathy: from Ion Channel Dysfunction To Clinical Disease. Current Cardiology Reports, 27(1), Article 138. https://doi.org/10.1007/s11886-025-02298-5