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Uyên Châu Nguyên wins UM Dissertation Prize 2025

Uyên Châu Nguyên wins UM Dissertation Prize 2025

29 January 2026

During the Dies Natalis of Maastricht University, Uyên Châu Nguyên received the UM Dissertation Prize 2025.

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Global research network launched to study menopause and heart health

Global research network launched to study menopause and heart health

20 January 2026

Ten international health research funders, including the Dutch Heart Foundation, are investing $10 million in a new global research network to improve early prevention of cardiovascular disease in women. The initiative focuses on understanding how menopause affects heart health and how early intervention can reduce risk.

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Carim Maastricht
Carim Maastricht

Martijn Brouwers

Professor

Dr Martijn Brouwers obtained his MD degree (with honours) in 2002, after which he started his PhD project that focused on hepatic steatosis in familial combined hyperlipidemia. In 2006, he worked as a trainee at the Department of Internal Medicine and Endocrinology. Since 2012, he has been a staff member (internist-endocrinologist) at Maastricht UMC+ and in 2019 he was appointed as the head of the division of Endocrinology and Metabolic Disease.

His research focusses on the cardiometabolic consequences of nonalcoholic fatty liver disease (NAFLD). NAFLD consists of a histological spectrum comprising simple steatosis, steatohepatitis (NASH), fibrosis and cirrhosis. Evidence is accumulating that NAFLD is not only a liver disease per se, it is also a risk factor for type 2 diabetes, chronic kidney disease and cardiovascular disease. This research line aims to elucidate the exact mechanistic link between NAFLD and these systemic diseases. For this, a diverse set of studies is used, ranging from (genetic) epidemiology, to ‘human knockout’ models, to randomised controlled trials and experimental animal work. This research is in part funded by the Dutch Heart Foundation, the Dutch Diabetes Foundation and the European Foundation for the Study of Diabetes.

Brouwers pasfoto

Department ofInternal Medicine
P. Debeyelaan 25, 6229 HX Maastricht 
PO Box 5800, 6202 AZ Maastricht
T: +31(0)43 388 70 19

  • 2026
    • Dimitropoulou, N. M., Beran, M., Eussen, S. J. P. M., Dingena, C. F., Dagnelie, P. C., Van Der Kallen, C. J. H., Koster, A., Van Greevenbroek, M. M. J., Brouwers, M. C. G. J., Schram, M. T., & de Galan, B. E. (2026). Liver fat content is not elevated in people with type 1 diabetes: the Maastricht Study. Diabetologia, 69(2), 364-373. https://doi.org/10.1007/s00125-025-06597-y
  • 2025
    • van Oeteren, M. A. J., De Groot, D. M., Buziau, A. M., Scheijen, J. L. J. M., van de Waarenburg, M. P. H., Kroon, A. A., Eussen, S. J. P. M., Dagnelie, P. C., Van Greevenbroek, M. M. J., Houben, A. J. H. M., Meex, S. J. R., Schalkwijk, C. G., & Brouwers, M. C. G. J. (2025). The effects of dietary fructose on blood pressure are modified by the food matrix. Clinical Nutrition, 55, 134-140. https://doi.org/10.1016/j.clnu.2025.10.017
    • Brouwers, M. C. G. J., Klop, B., Ribalta, J., & Cabezas, M. C. (2025). Familial Combined Hyperlipidemia: Myth or Reality?Current Atherosclerosis Reports, 27(1), Article 45. https://doi.org/10.1007/s11883-025-01289-9
    • Visker, V. P., Kvist, A. V., Vestergaard, P., van den Bergh, J. P., Brouwers, M. C. J. G., Wyers, C. E., & Driessen, J. H. M. (2025). Fracture trends in Denmark from 1997 to 2021. Osteoporosis International. Advance online publication. https://doi.org/10.1007/s00198-025-07746-0
    • Chen, H., Simons, P. I. H. G., Simons, N., van de Waarenburg, M. P. H., Bons, J. A. P., van der Ploeg, E. M. C. L., Feskens, E. J. M., Schalkwijk, C. G., & Brouwers, M. C. G. J. (2025). Effects of glucose and fructose supplementation on serum sex hormone-binding globulin and testosterone levels: post-hoc analysis of a double-blind randomized controlled trial. Clinical Nutrition ESPEN, 69, 384-388. https://doi.org/10.1016/j.clnesp.2025.07.1123
    • Ren, Z., Wesselius, A., Kooi, M. E., van Greevenbroek, M., Dagnelie, P., Berendschot, T. T. J. M., Kroon, A. A., Houben, A. J. H. M., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2025). Steatotic liver disease interacts with a polygenic risk score for triglyceride clearance to impact the risk of hypertriglyceridaemia: The Maastricht Study. Diabetologia, 68(10), 2217-2226. https://doi.org/10.1007/s00125-025-06479-3
    • Tichler, A., Hertroijs, D. F. L., van Mastrigt, G. A. P. G., Brouwers, M. C. G. J., Ruwaard, D., & Elissen, A. M. J. (2025). Evaluating the feasibility of study methods for a future trial-based economic evaluation of a multistage shared decision-making program for type 2 diabetes mellitus: Protocol for a cluster-randomized controlled pilot study. PLOS ONE, 20(8), Article e0300944. https://doi.org/10.1371/journal.pone.0300944
    • Langeveld, M., Brouwers, M. C. G. J., van Dussen, L., Koens, L. H., Langendonk, J. G. L., & Janssen, M. C. H. (2025). Erfelijke metabole ziekten bij volwassenen. Nederlands Tijdschrift voor Geneeskunde, 169, Article D8476. https://www.ntvg.nl/artikelen/erfelijke-metabole-ziekten-bij-volwassenen
    • Janssen, L. E. F., Hiligsmann, M., Timmer, C., van der Ploeg, L. M. C., Kerckhove, K. V., Cox, T., Heras, J. D. L., Cassiman, D., & Brouwers, M. C. G. J. (2025). Treatment preferences of adult patients with hereditary fructose intolerance: A discrete choice experiment. Molecular Genetics and Metabolism, 145(4), Article 109169. https://doi.org/10.1016/j.ymgme.2025.109169
    • van Bree, B. E., van der Heijden, D. M. B., van Golde, R. J. T., Brouwers, M. C. G. J., Spaanderman, M. E. A., & Valkenburg, O. (2025). Sex hormone-binding globulin as a biomarker for metabolic risk in European women with polycystic ovary syndrome. Gynecological Endocrinology, 41(1), Article 2500462. Advance online publication. https://doi.org/10.1080/09513590.2025.2500462
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