Robert van Oostenbrugge

Professor

Robert van Oostenbrugge is Professor of Neurology, with a chair on Vascular Neurology, head of the Department of Neurology (UM); principal Investigator of CARIM and programme leader of Vascular Neurology / Stroke. Robert (R.J.) van Oostenbrugge; (born Havelte, 1965) obtained a MD at the Maastricht University in Maastricht (1990). He was registered as neurologist in 2000 and obtained a PhD in 1999 (University Maastricht, Maastricht). In 2013, he was appointed Professor of Neurology chair of the Department of Neurology at Maastricht University. He is member of the Centers of Excellence in Neurodegeneration initiative and of the JPND funded initiative HARNESS aiming to harmonise imaging standards in vascular dementia, member of the board of the Dutch Section of Vascular Neurology.

Department of Neurology
P. Debyelaan 25, 6229 HX Maastricht
PO Box 5800, 6202 AZ Maastricht
T: +31 (0)43 387 70 58

2026
- Doheim, M. F., Knapen, R. R. M. M., Dippel, D. W. J., Staals, J., Hofmeijer, J., van Es, A. C. G. M., Coutinho, J. M., van der Leij, C., Nogueira, R. G., van Oostenbrugge, R. J., van Zwam, W. H., & MR CLEAN Registry Investigators (2026). Association of anesthesia strategies with outcomes in endovascular treatment for distal and medium vessel occlusions: A propensity score-matched analysis of the MR CLEAN registry and meta-analysis. European Stroke Journal, 11(1), Article 23969873251352406. https://doi.org/10.1177/23969873251352406
- Wang, Y., Luijten, S. P. R., Bos, D., Mulder, I. A., Kappelhof, M., Westendorp, W. F., Emmer, B. J., Roosendaal, S. D., Roos, Y. B. W. M., Van Den Wijngaard, I. R., Van Oostenbrugge, R. J., Van De Beek, D., Coutinho, J. M., & MR CLEAN Registry Investigators (2026). Association of CRP levels and clinical and radiological outcomes in patients with large-vessel occlusion stroke: A MR CLEAN Registry study. European Stroke Journal, 11(1), Article 23969873251357134. https://doi.org/10.1177/23969873251357134
- Reitsma, F. J., van Kuijk, S. M. J., Werring, D. J., Banerjee, G., Cordonnier, C., Kaaouana, O., Puy, L., Biffi, A., Viswanathan, A., van Oostenbrugge, R. J., Staals, J., & Rouhl, R. P. W. (2026). Development and external validation of the LEAN score to predict late seizures after intracerebral haemorrhage. European Stroke Journal, 11(1), Article 23969873251350882. https://doi.org/10.1177/23969873251350882
- Kersten, C., Zandbergen, A. A. M., Olthuis, S. G. H., Van Zwam, W., Hofmeijer, J., Emmer, B. J., Hoving, J. W., van Oostenbrugge, R. J., & den Hertog, H. (2026). Hyperglycaemia does not modify the efficacy of endovascular therapy in the late time window (6-24 hours). International journal of stroke, 21(1), 138-145. https://doi.org/10.1177/17474930251358824
- Bierens, J., Ament, S. M. C., Truijman, M. T. B., de Borst, G. J., Nederkoorn, P. J., Bos, D., Joore, M. A., Postma, A. A., Kooi, M. E., van Oostenbrugge, R. J., Smits, L. J. M., & IMPROVE Investigators (2026). Plaque Magnetic Resonance Imaging Based Decision Rule for the Selection of Symptomatic Patients for Carotid Revascularisation: Clinician Perspectives on Acceptability and Implementation Barriers in the Netherlands. European Journal of Vascular and Endovascular Surgery, 71(1), 5-11. https://doi.org/10.1016/j.ejvs.2025.08.022
2025
- van Kempen, E. J., Schellekens, M. M. I., Verhoeven, J. I., Ekker, M. S., Verburgt, E., Immens, M. H. M., Hilkens, N. A., Boot, E. M., van Alebeek, M. E., Brouwers, P. J. A. M., Arntz, R. M., van Dijk, G. W., Gons, R. A. R., van Uden, I. W. M., den Heijer, T., van Tuijl, J. H., de Laat, K. F., van Norden, A. G. W., Vermeer, S. E., ... Tuladhar, A. M. (2025). Prevalence and Factors Associated With Atrial Fibrillation Among Young Patients With Ischemic Stroke. Journal of the American Heart Association, 14(24), Article e043996. https://doi.org/10.1161/JAHA.125.043996
- Knapen, R. R. M. M., Doheim, M. F., Audebert, H. J., Mont'Alverne, F., Puetz, V., Michel, P., Liu, X., Dai, Q., Hu, W., Tao, C., Liu, R., Xu, P., Li, C., Ji, X., Jovin, T. G., van der Leij, C., van Oostenbrugge, R. J., van Zwam, W. H., Nogueira, R. G., ... VERITAS Collaborators (2025). Intravenous Thrombolysis Prior to Endovascular Treatment in Basilar Artery Occlusions: A Patient Pooled Analysis of Four Randomized Controlled Trials. Cardiovascular and Interventional Radiology, 48(12), 1869-1877. https://doi.org/10.1007/s00270-025-04251-z
- Dassen, S., Van Es, A., Roozenbeek, B., Van De Graaf, R., Roos, Y., Majoie, C., Ghariq, E., Kruyt, N., Fischer, U., Van Oostenbrugge, R., Van Zwam, W., & Staals, J. (2025). Time to Endovascular Treatment and Clinical Outcome in Acute Ischemic Stroke With M2-Segment Occlusion. Journal of the American Heart Association, 14(22), 1-10. Article e043984. https://doi.org/10.1161/JAHA.125.043984
- Bierens, J., Speetjens, I., Van Oostenbrugge, R. J., Smits, L. J. M., Kooi, M. E., & Truijman, M. T. B. (2025). Systematic Review of the Discrepancies Between Guideline Recommendations on Carotid Revascularization in Patients with Symptomatic Carotid Artery Disease. Stroke: vascular and interventional neurology, 5(6), Article e001844. https://doi.org/10.1161/SVIN.125.001844
- Verstappen, D., de Jong, J. J. A., Voorter, P. H. M., van Dinther, M., van Oostenbrugge, R. J., Staals, J., Jansen, J. F. A., & Backes, W. H. (2025). DCE-MRI reveals spatial pattern in heterogeneous blood-brain barrier leakage within white matter in cerebral small vessel disease. Journal of Cerebral Blood Flow and Metabolism, 45(11), 2104-2114. Article 0271678X251364151. https://doi.org/10.1177/0271678X251364151

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Robert van Oostenbrugge

Professor