Eline Kooi

Professor

Prof. Eline Kooi obtained a Master degree in Physics (University of Amsterdam, 1995) and a PhD degree in Molecular Physics at the same university (1999). She was trained in Medical Physics, specialisation Radiology, at Maastricht UMC from 1999-2004. Since 2004 she is a registered Medical Physicist at Maastricht UMC+. Presently, she is a Professor of Medical Physics, especially vascular imaging, at the Department of Radiology and Nuclear Medicine within CARIM.

Her research is focussed on sophisticated multi-modality cardiovascular imaging. Her group is at the international forefront of developing and evaluating imaging techniques to study plaque vulnerability. She has focussed on cutting edge imaging of the hallmarks of high-risk plaques in animals and patients. She was the first to demonstrate that plaque inflammation can be visualised in humans. Her group has the unique position of multi-modality imaging of the vessel wall (PET/MRI, ultrasound, CT) in different vascular beds (carotid and coronary arteries, aorta). She has performed numerous MR Spectroscopy studies on lipid metabolism, also in the heart. Recently, she has expanded her research towards cardiac MRI (perfusion MRI, T1 mapping).

She is a leading member of the steering committee of a multi-centre trial to determine the clinical value of plaque imaging (PARISK) and she coordinates plaque imaging within the European Carotid Surgery Trial-2 (ECST-2). She has published >100 scientific publications in international peer-reviewed journals. She has successfully completed supervision of 12 PhD students. Currently, she is supervising 6 PhD students and one post-doc student. She is frequently invited as invited speaker and/or moderator at the leading international conferences in her field. She has received numerous research grants.

Department of Radiology and Nuclear Medicine
Universiteitssingel 50, 6229 ER Maastricht
PO Box 616, 6200 MD Maastricht
Room number: H1.328
T: +31(0)43 387 49 11

 

  • 2022
    • Raafs, A. G., Ghossein, M. A., Brandt, Y., Henkens, M. T. H. M., Kooi, M. E., Vernooy, K., Spaanderman, M. E. A., Gerretsen, S., van Santen, S., Driessen, R. G. H., Knackstedt, C., van der Horst, I. C. C., van Bussel, B. C. T., Heymans, S. R. B., Ghossein-Doha, C., & MaastrICCht Collaborators (2022). Cardiovascular outcome 6 months after severe coronavirus disease 2019 infection. Journal of Hypertension, 40(7), 1278-1287. https://doi.org/10.1097/hjh.0000000000003110
    • de Vries, J. J., Autar, A. S. A., van Dam-Nolen, D. H. K., Donkel, S. J., Kassem, M., van der Kolk, A. G., van Velzen, T. J., Kooi, M. E., Hendrikse, J., Nederkoorn, P. J., Bos, D., van der Lugt, A., de Maat, M. P. M., & van Beusekom, H. M. M. (2022). Association between plaque vulnerability and neutrophil extracellular traps (NETs) levels: The Plaque At RISK study. PLOS ONE, 17(6), Article e0269805. https://doi.org/10.1371/journal.pone.0269805
    • Aizaz, M., van der Pol, J. A. J., Wierts, R., Zwart, H., van der Werf, A. J., Wildberger, J. E., Bucerius, J. A., Moonen, R. P. M., & Kooi, M. E. (2022). Evaluation of a Dedicated Radiofrequency Carotid PET/MRI Coil. Journal of Clinical Medicine, 11(9), Article 2569. https://doi.org/10.3390/jcm11092569
    • Buziau, A. M., Eussen, S. J. P. M., Kooi, M. E., van der Kallen, C. J. H., van Dongen, M. C. J. M., Schaper, N. C., Henry, R. M. A., Schram, M. T., Dagnelie, P. C., van Greevenbroek, M. M. J., Wesselius, A., Bekers, O., Meex, S. J. R., Schalkwijk, C. G., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2022). Fructose Intake From Fruit Juice and Sugar-Sweetened Beverages Is Associated With Higher Intrahepatic Lipid Content: The Maastricht Study. Diabetes Care, 45(5), 1116-1123. https://doi.org/10.2337/dc21-2123
    • Holtackers, R. J., Emrich, T., Botnar, R. M., Kooi, M. E., Wildberger, J. E., & Kreitner, K.-F. (2022). Late Gadolinium Enhancement Cardiac Magnetic Resonance Imaging: From Basic Concepts to Emerging Methods. RöFo-Fortschritte auf dem Gebiet der Röntgenstrahlen und der Bildgebenden Verfahren, 194(05), 491-504. https://doi.org/10.1055/a-1718-4355
    • Paraskevas, K. I., Mikhailidis, D. P., Antignani, P. L., Baradaran, H., Bokkers, R. P. H., Cambria, R. P., Dardik, A., Davies, A. H., Eckstein, H. H., Faggioli, G., Fernandes, J. F. E., Fraedrich, G., Geroulakos, G., Gloviczki, P., Golledge, J., Gupta, A., Jezovnik, M. K., Kakkos, S. K., Katsiki, N., ... Chaturvedi, S. (2022). Optimal management of asymptomatic carotid stenosis in 2021: the jury is still out. An international, multispecialty, expert review and position statement. International Angiology, 41(2), 158-169. https://doi.org/10.23736/S0392-9590.21.04825-2
    • Brandt, Y., Ghossein-Doha, C., Gerretsen, S. C., Spaanderman, M. E. A., & Kooi, M. E. (2022). Noninvasive Cardiac Imaging in Formerly Preeclamptic Women for Early Detection of Subclinical Myocardial Abnormalities: A 2022 Update. Biomolecules, 12(3), Article 415. https://doi.org/10.3390/biom12030415
    • Crombag, G. A. J. C., Aizaz, M., Schreuder, F. H. B. M., Benali, F., Van Dam-Nolen, D. H. K., Liem, M. I. L., Lucci, C., van der Steen, A. F., Daemen, M. J. A. P., Mess, W. H., van der Lugt, A., Nederkoorn, P. J., Hendrikse, J., Hofman, P. A. M., van Oostenbrugge, R. J., Wildberger, J. E., & Kooi, M. E. (2022). Proximal Region of Carotid Atherosclerotic Plaque Shows More Intraplaque Hemorrhage: The Plaque at Risk Study. American Journal of Neuroradiology, 43(2), 265-271. https://doi.org/10.3174/ajnr.A7384
    • van Dam-Nolen, D. H. K., van Egmond, N. C. M., Dilba, K., Nies, K., van der Kolk, A. G., Liem, M. I., Kooi, M. E., Hendrikse, J., Nederkoorn, P. J., Koudstaal, P. J., van der Lugt, A., & Bos, D. (2022). Sex Differences in Plaque Composition and Morphology Among Symptomatic Patients With Mild-to-Moderate Carotic Artery Stenosis. Stroke, 53(2), 370-378. https://doi.org/10.1161/STROKEAHA.121.036564
    • Paraskevas, K. I., Mikhailidis, D. P., Baradaran, H., Bokkers, R. P. H., Davies, A. H., Eckstein, H. H., Faggioli, G., Fernandes, J. F. E., Gargiulo, M., Jawien, A., Jezovnik, M. K., Kakkos, S. K., Knoflach, M., Kooi, M. E., Lanza, G. O., Liapis, C. D., Loftus, I. M., Mansilha, A., Mechtouff, L., ... Gloviczki, P. (2022). The burden of carotid-related strokes. Annals of translational medicine, 10(3), Article 159. https://doi.org/10.21037/atm-2021-12
    • Paraskevas, K. I., Mikhailidis, D. P., Antignani, P. L., Baradaran, H., Bokkers, R. P. H., Cambria, R. P., Dardik, A., Davies, A. H., Eckstein, H. H., Faggioli, G., Fernande, J. F. E., Fraedrich, G., Geroulakos, G., Gloviczki, P., Golledge, J., Jezovnik, M. K., Kakkos, S. K., Katsiki, N., Knoflach, M., ... Chaturvedi, S. (2022). Optimal Management of Asymptomatic Carotid Stenosis in 2021: The Jury is Still Out. An International, Multispecialty, Expert Review and Position Statement. Journal of Stroke & Cerebrovascular Diseases, 31(1), Article 106182. https://doi.org/10.1016/j.jstrokecerebrovasdis.2021.106182
    • Paraskevas, K. I., Mikhailidis, D. P., Baradaran, H., Davies, A. H., Eckstein, H.-H., Faggioli, G., Fernandes, J. F. E., Gupta, A., Jezovnik, M. K., Kakkos, S. K., Katsiki, N., Kooi, M. E., Lanza, G., Liapis, C. D., Loftus, I. M., Millon, A., Nicolaides, A. N., Poredos, P., Pini, R., ... Chaturvedi, S. (2022). Optimal Management of Asymptomatic Carotid Stenosis: Counterbalancing the Benefits with the Potential Risks. Journal of Stroke, 24(1), 163-165. https://doi.org/10.5853/jos.2021.04420
    • Segers, F. M. E., Ruder, A. V., Westra, M. M., Lammers, T., Dadfar, S. M., Roemhild, K., Lam, T. S., Eline Kooi, M., Cleutjens, K. B. J. M., Verheyen, F. K., Schurink, G. W. H., Haenen, G. R., van Berkel, T. J. C., Bot, I., Halvorsen, B., Sluimer, J. C., & Biessen, E. A. L. (2022). Magnetic resonance imaging contrast-enhancement with superparamagnetic iron oxide nanoparticles amplifies macrophage foam cell apoptosis in human and murine atherosclerosis. Cardiovascular Research, 118, 3346-3359. https://doi.org/10.1093/cvr/cvac032
  • 2021
    • Paraskevas, K. I., Mikhailidis, D. P., Baradaran, H., Davies, A. H., Eckstein, H. H., Faggioli, G., Fernandes, J. F. E., Gupta, A., Jezovnik, M. K., Kakkos, S. K., Katsiki, N., Kooi, M. E., Lanza, G., Liapis, C. D., Loftus, I. M., Millon, A., Nicolaides, A. N., Poredos, P., Pini, R., ... Chaturvedi, S. (2021). Management of patients with asymptomatic carotid stenosis may need to be individualized: a multidisciplinary call for action. Republication of J Stroke 2021;23:202-12. International Angiology, 40(6), 487-496. https://doi.org/10.23736/S0392-9590.21.04751-9
    • Dilba, K., van Dam-Nolen, D. H. K., Korteland, S. A., van der Kolk, A. G., Kassem, M., Bos, D., Koudstaal, P. J., Nederkoorn, P. J., Hendrikse, J., Kooi, M. E., Gijsen, F. J. H., van der Steen, A. F. W., van der Lugt, A., & Wentzel, J. J. (2021). The Association Between Time-Varying Wall Shear Stress and the Development of Plaque Ulcerations in Carotid Arteries From the Plaque at Risk Study. Frontiers in Cardiovascular Medicine, 8, Article 732646. https://doi.org/10.3389/fcvm.2021.732646
    • Saba, L., Brinjikji, W., Spence, J. D., Wintermark, M., Castillo, M., Borst, G. J. D., Yang, Q., Yuan, C., Buckler, A., Edjlali, M., Saam, T., Saloner, D., Lal, B. K., Capodanno, D., Sun, J., Balu, N., Naylor, R., v. d. Lugt, A., Wasserman, B. A., ... Moody, A. R. (2021). Roadmap Consensus on Carotid Artery Plaque Imaging and Impact on Therapy Strategies and Guidelines: An International, Multispecialty, Expert Review and Position Statement. American Journal of Neuroradiology, 42(9), 1566-1575. https://doi.org/10.3174/ajnr.A7223
    • Camarasa , R., Bos, D., Hendrikse, J., Nederkoorn, P. J., Kooi, E., van der Lugt, A., & de Bruijne, M. (2021). A Quantitative Comparison of Epistemic Uncertainty Maps Applied to Multi-Class Segmentation. The Journal of Machine Learning for Biomedical Imaging, 013, 1-39 . https://doi.org/10.59275/j.melba.2021-ec49
    • Dilba, K., Van Dam-Nolen, D. H. K., Crombag, G. A. J. C., van der Kolk, A. G., Koudstaal, P. J., Nederkoorn, P. J., Hendrikse, J., Kooi, M. E., van der Steen, A. F. W., Wentzel, J. J., van der Lugt, A., & Bos, D. (2021). Dolichoarteriopathies of the extracranial internal carotid artery: The Plaque At RISK study. European Journal of Neurology, 28(9), 3133-3138. https://doi.org/10.1111/ene.14982
    • Nies, K. P. H., Smits, L. J. M., Kassem, M., Nederkoorn, P. J., van Oostenbrugge, R. J., & Kooi, M. E. (2021). Emerging Role of Carotid MRI for Personalized Ischemic Stroke Risk Prediction in Patients With Carotid Artery Stenosis. Frontiers in Neurology, 12, Article 718438. https://doi.org/10.3389/fneur.2021.718438
    • Holtackers, R. J., Van De Heyning, C. M., Chiribiri, A., Wildberger, J. E., Botnar, R. M., & Kooi, M. E. (2021). Dark-blood late gadolinium enhancement cardiovascular magnetic resonance for improved detection of subendocardial scar: a review of current techniques. Journal of Cardiovascular Magnetic Resonance, 23(1), Article 96. https://doi.org/10.1186/s12968-021-00777-6
    • Van Dam-Nolen, D. H. K., van Dijk, A. C., Crombag, G. A. J. C., Lucci, C., Kooi, M. E., Hendrikse, J., Nederkoorn, P. J., Daemen, M. J. A. P., van der Steen, A. F. W., Koudstaal, P. J., Kronenberg, F., van Lennep, J. E. R., Mulder, M. T., & van der Lugt, A. (2021). Lipoprotein(a) levels and atherosclerotic plaque characteristics in the carotid artery: The Plaque at RISK (PARISK) study. Atherosclerosis, 329, 22-29. https://doi.org/10.1016/j.atherosclerosis.2021.06.004
    • Paraskevas, K., Mikhailidis, D. P., Baradaran, H., Davies, A. H., Eckstein, H.-H., Faggioli, G., Fernandes, J. F. E., Gupta, A., Jezovnik, M. K., Kakkos, S. K., Katsiki, N., Kooi, M. E., Lanza, G., Liapis, C. D., Loftus, I. M., Millon, A., Nicolaides, A. N., Poredos, P., Pini, R., ... Chaturvedi, S. (2021). Management of Patients with Asymptomatic Carotid Stenosis May Need to Be Individualized: A Multidisciplinary Call for Action. Journal of Stroke, 23(2), 202-212. https://doi.org/10.5853/jos.2020.04273
    • Best, J. G., Ambler, G., Wilson, D., Lee, K. J., Lim, J. S., Shiozawa, M., Koga, M., Li, L. X., Lovelock, C., Chabriat, H., Hennerici, M., Wong, Y. K., Mak, H. K. F., Prats-Sanchez, L., Martinez-Domeno, A., Inamura, S., Yoshifuji, K., Arsava, E. M., Horstmann, S., ... Werring, D. J. (2021). Development of imaging-based risk scores for prediction of intracranial haemorrhage and ischaemic stroke in patients taking antithrombotic therapy after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies. Lancet Neurology, 20(4), 294-303. https://doi.org/10.1016/S1474-4422(21)00024-7
    • Florea, A., Kooi, M. E., Mess, W., Schurgers, L. J., Bucerius, J., & Mottaghy, F. M. (2021). Effects of Combined Vitamin K2 and Vitamin D3 Supplementation on Na[18F]F PET/MRI in Patients with Carotid Artery Disease: The INTRICATE Rationale and Trial Design. Nutrients, 13(3), Article 994. https://doi.org/10.3390/nu13030994
    • van Haare, J., Kooi, M. E., van Teeffelen, J. W. G. E., Vink, H., Slenter, J., Cobelens, H., Strijkers, G. J., Koehn, D., Post, M. J., & van Bilsen, M. (2021). Correction to: Metformin and sulodexide restore cardiac microvascular perfusion capacity in diet‑induced obese rats. Cardiovascular Diabetology, 20(1), Article 53. https://doi.org/10.1186/s12933-021-01240-7
    • van Haare, J., Kooi, M. E., Vink, H., Post, M. J., van Teeffelen, J. W. G. E., Slenter, J., Munts, C., Cobelens, H., Strijkers, G. J., Koehn, D., & van Bilsen, M. (2021). Correction to: Early impairment of coronary microvascular perfusion capacity in rats on a high fat diet. Cardiovascular Diabetology, 20(1), Article 51. https://doi.org/10.1186/s12933-021-01239-0
    • Dilba, K., van Dijk, A. C., Crombag, G. A. J. C., van der Steen, A. F. W., Daemen, M. J., Koudstaal, P. J., Nederkoorn, P. J., Hendrikse, J., Kooi, M. E., van der Lugt, A., & Wentzel, J. J. (2021). Association between Intraplaque Hemorrhage and Vascular Remodeling in Carotid Arteries: The Plaque at RISK (PARISK) Study. Cerebrovascular Diseases, 50(1), 94-99. https://doi.org/10.1159/000511935
    • Simons, N., Veeraiah, P., Simons, P. I. H. G., Schaper, N. C., Kooi, M. E., Schrauwen-Hinderling, V. B., Feskens, E. J. M., van der Ploeg, E. M. C., Van den Eynde, M. D. G., Schalkwijk, C. G., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2021). Effects of fructose restriction on liver steatosis (FRUITLESS); a double-blind randomized controlled trial. American Journal of Clinical Nutrition, 113(2), 391-400. https://doi.org/10.1093/ajcn/nqaa332
    • Dilba, K., van Dam-Nolen, D. H. K., van Dijk, A. C., Kassem, M., van der Steen, A. F. W., Koudstaal, P. J., Nederkoorn, P. J., Hendrikse, J., Kooi, M. E., Wentzel, J. J., & van der Lugt, A. (2021). Plaque Composition as a Predictor of Plaque Ulceration in Carotid Artery Atherosclerosis: The Plaque At RISK Study. American Journal of Neuroradiology, 42(1), 144-151. https://doi.org/10.3174/ajnr.A6868
  • 2020
    • Dweck, M. R., Maurovich-Horvat, P., Leiner, T., Cosyns, B., Fayad, Z. A., Gijsen, F. J. H., Van der Heiden, K., Kooi, M. E., Maehara, A., Muller, J. E., Newby, D. E., Narula, J., Pontone, G., Regar, E., Serruys, P. W., van der Steen, A. F. W., Stone, P. H., Waltenberger, J. L., Yuan, C., ... Back, M. (2020). Contemporary rationale for non-invasive imaging of adverse coronary plaque features to identify the vulnerable patient: a Position Paper from the European Society of Cardiology Working Group on Atherosclerosis and Vascular Biology and the European Association of Cardiovascular Imaging. European Heart Journal Cardiovascular Imaging, 21(11), 1177-1183. https://doi.org/10.1093/ehjci/jeaa201
    • Saba, L., Moody, A. R., Saam, T., Kooi, M. E., Wasserman, B. A., Staub, D., van der Lugt, A., DeMarco, J. K., Saloner, D., Wintermark, M., & Gupta, A. (2020). Vessel Wall-Imaging Biomarkers of Carotid Plaque Vulnerability in Stroke Prevention Trials A Viewpoint From the Carotid Imaging Consensus Group. JACC-Cardiovascular Imaging, 13(11), 2445-2456. https://doi.org/10.1016/j.jcmg.2020.07.046
    • Kassem, M., Florea, A., Mottaghy, F. M., van Oostenbrugge, R., & Kooi, M. E. (2020). Magnetic resonance imaging of carotid plaques: current status and clinical perspectives. Annals of translational medicine, 8(19), Article 1266. https://doi.org/10.21037/atm-2020-cass-16
    • Wouters, K., Kusters, Y. H. A. M., Bijnen, M., Wetzels, S., Zhang, X., Linssen, P. B. C., Gaens, K., Houben, A. J. H. M., Joris, P. J., Plat, J., Kooi, M. E., van der Kallen, C. J. H., Mensink, R. P., Verboven, K., Jocken, J., Hansen, D., Blaak, E. E., Ehlers, F. A. I., Wieten, L., ... Schalkwijk, C. G. (2020). NK cells in human visceral adipose tissue contribute to obesity-associated insulin resistance through low-grade inflammation. Clinical and Translational Medicine, 10(6), Article e192. https://doi.org/10.1002/ctm2.192
    • Aizaz, M., Moonen, R. P. M., van der Pol, J. A. J., Prieto, C., Botnar, R. M., & Kooi, M. E. (2020). PET/MRI of atherosclerosis. Cardiovascular Diagnosis and Therapy, 10(4), 1120-1139. https://doi.org/10.21037/cdt.2020.02.09
    • Schindler, A., Schinner, R., Altaf, N., Hosseini, A. A., Simpson, R. J., Esposito-Bauer, L., Singh, N., Kwee, R. M., Kurosaki, Y., Yamagata, S., Yoshida, K., Miyamoto, S., Maggisano, R., Moody, A. R., Poppert, H., Kooi, M. E., Auer, D. P., Bonati, L. H., & Saam, T. (2020). Prediction of Stroke Risk by Detection of Hemorrhage in Carotid Plaques Meta-Analysis of Individual Patient Data. JACC-Cardiovascular Imaging, 13(2), 395-406. https://doi.org/10.1016/j.jcmg.2019.03.028
  • 2019
    • Simons, N., Debray, F.-G., Schaper, N. C., Kooi, M. E., Feskens, E. J. M., Hollak, C. E. M., Lindeboom, L., Koek, G. H., Bons, J. A. P., Lefeber, D. J., Hodson, L., Schalkwijk, C. G., Stehouwer, C. D. A., Cassiman, D., & Brouwers, M. C. G. J. (2019). Patients With Aldolase B Deficiency Are Characterized by Increased Intrahepatic Triglyceride Content. Journal of Clinical Endocrinology & Metabolism, 104(11), 5056-5064. https://doi.org/10.1210/jc.2018-02795
    • Wilson, D., Ambler, G., Lee, K.-J., Lim, J.-S., Shiozawa, M., Koga, M., Li, L., Lovelock, C., Chabriat, H., Hennerici, M., Wong, Y. K., Mak, H. K. F., Prats-Sanchez, L., Martinez-Domeno, A., Inamura, S., Yoshifuji, K., Arsava, E. M., Horstmann, S., Purrucker, J., ... Werring, D. J. (2019). Cerebral microbleeds and stroke risk after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies. Lancet Neurology, 18(7), 653-665. https://doi.org/10.1016/S1474-4422(19)30197-8
    • Telgenkamp, I., Kusters, Y. H. A. M., Schalkwijk, C. G., Houben, A. J. H. M., Kooi, M. E., Lindeboom, L., Bons, J. A. P., Schaper, N. C., Joris, P. J., Plat, J., Mensink, R. P., Stehouwer, C. D. A., & Brouwers, M. C. G. J. (2019). Contribution of Liver Fat to Weight Loss-Induced Changes in Serum Hepatokines: A Randomized Controlled Trial. Journal of Clinical Endocrinology & Metabolism, 104(7), 2719-2727. https://doi.org/10.1210/jc.2018-02378
    • van Dijk, A. C., Donkel, S. J., Zadi, T., Sonneveld, M. A. H., Schreuder, F. H. B. M., Chohan, M. F., Koudstaal, P. J., Leebeek, F. W. G., Saxena, R., Hendrikse, J., Kooi, M. E., van der Lugt, A., & de Maat, M. P. M. (2019). Association between fibrinogen and fibrinogen γ’ and atherosclerotic plaque morphology and composition in symptomatic carotid artery stenosis: Plaque-At-RISK study. Thrombosis Research, 177, 130-135. https://doi.org/10.1016/j.thromres.2019.02.030
    • Crombag, G. A. J. C., van Hoof, R. H. M., Holtackers, R. J., Schreuder, F. H. B. M., Truijman, M. T. B., Schreuder, T. A. H. C. M. L., van Orshoven, N. P., Mess, W. H., Hofman, P. A. M., van Oostenbrugge, R. J., Wildberger, J. E., & Kooi, M. E. (2019). Symptomatic Carotid Plaques Demonstrate Less Leaky Plaque Microvasculature Compared With the Contralateral Side: A Dynamic Contrast-Enhanced Magnetic Resonance Imaging Study. Journal of the American Heart Association, 8(8), Article 011832. https://doi.org/10.1161/JAHA.118.011832
    • Crombag, G. A. J. C., Schreuder, F. H. B. M., van Hoof, R. H. M., Truijman, M. T. B., Wijnen, N. J. A., Voo, S. A., Nelemans, P. J., Heeneman, S., Nederkoorn, P. J., Daemen, J.-W. H., Daemen, M. J. A. P., Mess, W. H., Wildberger, J. E., van Oostenbrugge, R. J., & Kooi, M. E. (2019). Microvasculature and intraplaque hemorrhage in atherosclerotic carotid lesions: a cardiovascular magnetic resonance imaging study. Journal of Cardiovascular Magnetic Resonance, 21(1), Article 15. https://doi.org/10.1186/s12968-019-0524-9
  • 2018
    • Crombag, G. A. J. C., Spronk, H. M., Nelemans, P., Schreuder, F. H. B. M., Truijman, M. T. B., van Dijk, A. C., de Rotte, A. A. J., Liem, M. I., Daemen, M. J. A. P., van der Steen, A. F. W., Mess, W. H., Nederkoorn, P. J., Hendrikse, J., van der Lugt, A., Wildberger, J. E., ten Cate, H., van Oostenbrugge, R. J., & Kooi, M. E. (2018). No Association between Thrombin Generation and Intra-Plaque Haemorrhage in Symptomatic Carotid Atherosclerotic Plaques: The Plaque at RISK (PARISK) Study. Thrombosis and Haemostasis, 118(8), 1461-1469. https://doi.org/10.1055/s-0038-1666858
    • Saba, L., Yuan, C., Hatsukami, T. S., Balu, N., Qiao, Y., DeMarco, J. K., Saam, T., Moody, A. R., Li, D., Matouk, C. C., Johnson, M. H., Jager, H. R., Mossa-Basha, M., Kooi, M. E., Fan, Z., Saloner, D., Wintermark, M., Mikulis, D. J., Wasserman, B. A., & Vessel Wall Imaging Study (2018). Carotid Artery Wall Imaging: Perspective and Guidelines from the ASNR Vessel Wall Imaging Study Group and Expert Consensus Recommendations of the American Society of Neuroradiology. American Journal of Neuroradiology, 39(2), E9-E31. https://doi.org/10.3174/ajnr.A5488
  • 2017
    • Arnoldussen, C. W. K. P., Lam, Y., Ito, N., Winkens, B., Kooi, M. E., Wittens, C. H. A., & Wildberger, J. E. (2017). Gadobutrol versus gadofosveset-trisodium in MR venography of the lower extremities. European Radiology, 27(12), 4986-4994. https://doi.org/10.1007/s00330-017-4902-0
    • van Hoof, R. H. M., Voo, S. A., Sluimer, J. C., Wijnen, N. J. A., Hermeling, E., Schreuder, F. H. B. M., Truijman, M. T. B., Cleutjens, J. P. M., Daemen, M. J. A. P., Daemen, J.-W. H., van Oostenbrugge, R. J., Mess, W. H., Wildberger, J. E., Heeneman, S., & Kooi, M. E. (2017). Vessel Wall and Adventitial DCE-MRI Parameters Demonstrate Similar Correlations With Carotid Plaque Microvasculature on Histology. Journal of Magnetic Resonance Imaging, 46(4), 1053-1059. https://doi.org/10.1002/jmri.25648
    • Kusters, Y. H. A. M., Schalkwijk, C. G., Houben, A. J. H. M., Kooi, M. E., Lindeboom, L., 't Roodt, J. O., Joris, P. J., Plat, J., Mensink, R. P., Barrett, E. J., & Stehouwer, C. D. A. (2017). Independent tissue contributors to obesity-associated insulin resistance. JCI INSIGHT, 2(13), Article e89695. https://doi.org/10.1172/jci.insight.89695
    • van Hoof, R. H. M., Hermeling, E., Sluimer, J. C., Salzmann, J., Hoeks, A. P. G., Roussel, J., Daemen, M. J. A. P., Struijker-Boudier, H., Wildberger, J. E., Heeneman, S., & Kooi, M. E. (2017). Heart rate lowering treatment leads to a reduction in vulnerable plaque features in atherosclerotic rabbits. PLOS ONE, 12(6), Article 0179024. https://doi.org/10.1371/journal.pone.0179024
    • van Haare, J., Kooi, M. E., van Teeffelen, J. W. G. E., Vink, H., Slenter, J., Cobelens, H., Strijkers, G. J., Koehn, D., Post, M. J., & van Bilsen, M. (2017). Metformin and sulodexide restore cardiac microvascular perfusion capacity in diet-induced obese rats. Cardiovascular Diabetology, 16(1), Article 47. https://doi.org/10.1186/s12933-017-0525-7