Fabienne Magdelijns

Professor

Dr. Fabienne Magdelijns obtained her medical degree from Maastricht University in the Netherlands. Her research primarily focuses on healthcare-related adverse events, with a particular emphasis on the frail older population.

She completed her PhD under the supervision of Professor Dr. Coen Stehouwer, Dr. Patricia Stassen and Dr. Evelien Pijpers at the Department of Internal Medicine, Maastricht UMC+.

Dr. Magdelijns currently serves as an internist with a specialization in geriatric care at Maastricht UMC+. She leads both the General Internal Medicine subdivision and the Geriatric Medicine section.

Her current research centers on the DOAC-FRAIL study, which aims to improve the safe prescribing of direct oral anticoagulants (DOACs) in frail older patients. In December 2024, she was awarded a grant from the Netherlands Thrombosis Foundation to conduct a multinational randomized controlled trial. This study, set to commence after the summer of 2025, will evaluate the effectiveness of a Single Measurement and Adjustment Strategy for DOACs in this vulnerable population.

Department of Internal Medicine
Subdivision of General Internal Medicine
Section of Geriatric medicine
T: +31(0)43 388 71 95

  • 2025
    • Vleeshouwers, K., Bastings, J. J. C., Brüggemann, R., de Jong, M. J., van den Boogaart, M., Poeze, M., van Es, N., Hanssen, N. M. J., Brouns, S., Magdelijns, F., & Spaetgens, B. (2025). Antithrombotic Therapy and Mortality Risk in Older Adults with Hip Fractures. Journal of the American Medical Directors Association, 26(8), Article 105690. https://doi.org/10.1016/j.jamda.2025.105690
    • Nielen, J. T. H., van der Walle, K., Spronk, S., Magdelijns, F., Denig, P., & Karapinar, F. (2025). Real-World Complexity of Prescribing Cascades. Basic & Clinical Pharmacology & Toxicology, 137(1), Article e70063. https://doi.org/10.1111/bcpt.70063
    • Truijen, S., Austen, S., Magdelijns, F., Boonen, A., & van Onna, M. (2025). Getting prepared for the silver wave: challenges in conducting rheumatic and musculoskeletal disease research in older adults. RMD Open, 11(1), Article e005280. https://doi.org/10.1136/rmdopen-2024-005280
  • 2024
    • de Jong, M. J., Saadan, H., van der Hooft, B. H. M., Hellenbrand, D. L. S., Brüggemann, R. A. G., Ten Cate, H., van Kuijk, S. M. J., van Geel, R. M. J. M., Henskens, Y. M. C., Winckers, K., & Magdelijns, F. J. H. (2024). Intra-Individual Variability of Direct Oral Anticoagulant Levels in Frail Older Patients upon, during, and after Acute Hospitalization: the DOAC-FRAIL Study. Journal of the American Medical Directors Association, 25(12), Article 105280. https://doi.org/10.1016/j.jamda.2024.105280
    • de Jong, M. J., Saadan, H., Hellenbrand, D. L. S., Ten Cate, H., Spaetgens, B., Brüggemann, R. A. G., van Kuijk, S. M. J., Winckers, K., Henskens, Y. M. C., & Magdelijns, F. J. H. (2024). The DOAC-FRAIL study, evaluation of direct oral anticoagulant-levels in acutely admitted frail older patients: An exploratory study. Journal of the American Geriatrics Society, 72(7), 2249-2253. https://doi.org/10.1111/jgs.18894
    • Pijls, N., Joosten, H., Theunissen, M., van Leendert, J., Courtens, A., Magdelijns, F., & Everdingen, M. V. D. B.-V. (2024). Bedside palliative care and geriatric consultations: adherence rate in hospitalised patients. BMJ Supportive and Palliative Care, 14(2), e2011-e2018. https://doi.org/10.1136/spcare-2023-004453
  • 2023
    • Brys, A. D. H. M., Stehouwer, C. D. A., van de Weijer, C., & Magdelijns, F. (2023). Not all is what it seems like: Hypercalcemia in the older patient. Geriatrics & Gerontology International, 23(11), 879-880. https://doi.org/10.1111/ggi.14689
    • Dijk-Huisman, H. C. V., Senden, R., Smeets, M. H. H., Marcellis, R. G. J., Magdelijns, F. J. H., & Lenssen, A. F. (2023). The Effect of a Smartphone App with an Accelerometer on the Physical Activity Behavior of Hospitalized Patients: A Randomized Controlled Trial. Sensors, 23(21), Article 8704. https://doi.org/10.3390/s23218704
    • Koekenbier, E. L., Fohse, K., van de Maat, J. S., Oosterheert, J. J., van Nieuwkoop, C., Hoogerwerf, J. J., Grobusch, M. P., van den Bosch, M. A. A. J., van de Wijgert, J. H. H., Netea, M. G., Rosendaal, F. R., Bonten, M. J. M., Werkhoven, C. H. H. V., Magdelijns, F., Stehouwer, C., & BCG-PRIME study group (2023). Bacillus Calmette-Guérin vaccine for prevention of COVID-19 and other respiratory tract infections in older adults with comorbidities: a randomized controlled trial. Clinical Microbiology and Infection, 29(6), 781-788. https://doi.org/10.1016/j.cmi.2023.01.019
  • 2022
    • Magdelijns, F. J. H. (2022). Response to the Letter to the Editor. Journal of the American Medical Directors Association, 23(9), 1506-1506. https://doi.org/10.1016/j.jamda.2022.07.022
    • van Dijk-Huisman, H. C., Welters, M. H. P., Bijnens, W., van Kuijk, S. M. J., Magdelijns, F. J. H., de Bie, R. A., & Lenssen, A. F. (2022). Development and internal validation of a prediction model to identify older adults at risk of low physical activity levels during hospitalisation: a prospective cohort study. BMC Geriatrics, 22(1), Article 479. https://doi.org/10.1186/s12877-022-03146-9
    • Theunissen, M., Magdelijns, F. J. H., Janssen, D. J. A., Naaktgeboren, M. W., Courtens, A., van Kuijk, S. M. J., & van den Beuken-van Everdingen, M. H. J. (2022). The Surprise Question in Older Hospitalized Patients: To Use or Not to Use?Journal of the American Medical Directors Association, 23(5), 894-896.e1. https://doi.org/10.1016/j.jamda.2022.01.058
    • van Dijk-Huisman, H. C., Raeven-Eijkenboom, P. H., Magdelijns, F. J. H., Sieben, J. M., de Bie, R. A., & Lenssen, A. F. (2022). Barriers and enablers to physical activity behaviour in older adults during hospital stay: a qualitative study guided by the theoretical domains framework. BMC Geriatrics, 22(1), Article 314. https://doi.org/10.1186/s12877-022-02887-x
    • Henkens, M. T. H. M., Raafs, A. G., Verdonschot, J. A. J., Linschoten, M., van Smeden, M., Wang, P., van der Hooft, B. H. M., Tieleman, R., Janssen, M. L. F., Ter Bekke, R. M. A., Hazebroek, M. R., van der Horst, I. C. C., Asselbergs, F. W., Magdelijns, F. J. H., Heymans, S. R. B., & CAPACITY-COVID collaborative consortium (2022). Age is the main determinant of COVID-19 related in-hospital mortality with minimal impact of pre-existing comorbidities, a retrospective cohort study. BMC Geriatrics, 22(1), Article 184. https://doi.org/10.1186/s12877-021-02673-1
  • 2021
    • Naaktgeboren, M. W., Magdelijns, F. J. H., Janssen, D. J. A., & van den Beuken-van Everdingen, M. H. J. (2021). Added Value of Early Consultation of an Inpatient Palliative Care Team in Hospitalized Older Patients With High Symptom Burden: A Prospective Comparative Study. American Journal of Hospice & Palliative Medicine, 38(10), 1258-1264. Article 1049909120982606. https://doi.org/10.1177/1049909120982606
    • van Leendert, J. A. A., Linkens, A. E. M. J. H., Poeze, M., Pijpers, E., Magdelijns, F., Ten Broeke, R. H. M., & Spaetgens, B. (2021). Mortality in hip fracture patients after implementation of a nurse practitioner-led orthogeriatric care program: results of a 1-year follow-up. Age and Ageing, 50(5), 1744-1750. https://doi.org/10.1093/ageing/afab031
    • van Moerbeke, A., Magdelijns, F., Cleutjens, F., Boonen, A., & van Onna, M. (2021). Development and Evaluation of a Clinic for Elderly Patients with Rheumatoid Arthritis and Multimorbidity: A Pilot Study. ACR open rheumatology, 3(1), 34-40. https://doi.org/10.1002/acr2.11213
    • Theunissen, M., Rideaux-Seferina, S., Magdelijns, F. J., Janssen, D. J. A., & van den Beuken-van Everdingen, M. H. J. (2021). Local Oral Pilocarpine Drops for Relieving Xerostomia (Dry Mouth) in the Elderly: A Pilot Study. Journal of the American Medical Directors Association, 22(1), 185-186. https://doi.org/10.1016/j.jamda.2020.06.036
  • 2020
    • Bruggemann, R. A. G., Spaetgens, B., Gietema, H. A., Brouns, S. H. A., Stassen, P. M., Magdelijns, F. J., Rennenberg, R. J., Henry, R. M. A., Mulder, M. M. G., van Bussel, B. C. T., Schnabel, R. M., van der Horst, I. C. C., Wildberger, J. E., Stehouwer, C. D. A., & ten Cate, H. (2020). The prevalence of pulmonary embolism in patients with COVID-19 and respiratory decline: A three-setting comparison. Thrombosis Research, 196, 486-490. https://doi.org/10.1016/j.thromres.2020.10.012
    • Brouns, S. H., Bruggemann, R., Linkens, A. E. M. J. H., Magdelijns, F. J., Joosten, H., Heijnen, R., ten Cate-Hoek, A. J., Schols, J. M. G. A., ten Cate, H., & Spaetgens, B. (2020). Mortality and the Use of Antithrombotic Therapies Among Nursing Home Residents withCOVID-19. Journal of the American Geriatrics Society, 68(8), 1647-1652. https://doi.org/10.1111/jgs.16664
    • Warnier, R. M. J., van Rossum, E., van Kuijk, S. M. J., Magdelijns, F., Schols, J. M. G. A., & Kempen, G. I. J. M. (2020). Frailty screening in hospitalised older adults: How does the brief Dutch National Safety Management Program perform compared to a more extensive approach?Journal of Clinical Nursing, 29(7-8), 1064-1073. https://doi.org/10.1111/jocn.15148
  • 2017
    • Knippels, M. C. J., Essers, I. M. M., Magdelijns, F. J. H., & Van Twist, D. J. L. (2017). 'Ecstasy-light': Niet zo onschuldig als het lijkt. Nederlands Tijdschrift voor Geneeskunde, 161(27), Article d1356.
    • Hurkens, K. P. G. M., Mestres-gonzalvo, C., Wit, H. A. J. M. D., Janknegt, R., Verhey, F., Schols, J. M. G. A., Magdelijns, F., Stehouwer, C. D. A., Winkens, B., Mulder, W., & Kuy, P. H. M. V. D. (2017). Assessing the strengths and weaknesses of a computer assisted medication review in hospitalized patients. International Journal of Hospital Pharmacy, 2(6), 1-12. https://doi.org/10.28933/IJHP-2017-10-0101
  • 2016
    • Magdelijns, F. J. H., van Avesaath, R. E. M., Pijpers, E., Stehouwer, C. D. A., & Stassen, P. M. (2016). Health-care-related adverse events leading to admission in older individuals: incidence, predictive factors and consequences. European Journal of Public Health, 26(5), 743-748. https://doi.org/10.1093/eurpub/ckw021
    • Magdelijns, F. J. H., Schepers, L., Pijpers, E., Stehouwer, C. D. A., & Stassen, P. M. (2016). Unplanned readmissions in younger and older adult patients: the role of healthcare-related adverse events. European Journal of Medical Research, 21(1), Article 35. https://doi.org/10.1186/s40001-016-0230-0
  • 2015
    • Magdelijns, F. J. H., Pijpers, E., Rouhl, R. P. W., Hannemann, P. F. W., ten Broeke, R. H. M., Dings, J. T. A., Stehouwer, C. D. A., & Stassen, P. M. (2015). Acute Hospital Admissions Because of Health Care-Related Adverse Events: A Retrospective Study of 5 Specialist Departments. Journal of the American Medical Directors Association, 16(12), 1055-1061. https://doi.org/10.1016/j.jamda.2015.06.019
    • Magdelijns, F. J. H., Schepers, L., Pijpers, E., Stehouwer, C. D. A., & Stassen, P. M. (2015). The survival of patients admitted because of health-care-related adverse events is similar to that after admission for other reasons. European journal of internal medicine, 26(2), 146-147. https://doi.org/10.1016/j.ejim.2015.01.003
    • Magdelijns, F., van den Beuken-van Everdingen, M. H. J., Courtens, A., & Janssen, D. (2015). Behandeling van doorbraakpijn bij kanker. Nederlands Tijdschrift voor Geneeskunde, 159(3), Article A8121.
  • 2014
    • Magdelijns, F. J. H., Stassen, P. M., Stehouwer, C. D. A., & Pijpers, E. (2014). Direct health care costs of hospital admissions due to adverse events in the Netherlands. European Journal of Public Health, 24(6), 1028-1033. https://doi.org/10.1093/eurpub/cku037
  • 2013
    • Magdelijns, F. J. H., Gulikers, D., Pijpers, E., Koopmans, R. P., & Stassen, A. P. M. (2013). Registering complications at admission via the emergency department: an opportunity for improvement. Netherlands Journal of Medicine, 71(1), 44-49.
  • 2011
    • Magdelijns, F. J. H., Mommers, M., Penders, J., Smits, L., & Thijs, C. (2011). Folic Acid Use in Pregnancy and the Development of Atopy, Asthma, and Lung Function in Childhood. Pediatrics, 128(1), e135-e144. https://doi.org/10.1542/peds.2010-1690