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Tullemans, B. M. E., Nagy, M., Sabrkhany, S., Griffioen, A. W., Egbrink, M. G. A. O., Aarts, M., Heemskerk, J. W. M., & Kuijpers, M. J. E. (2018). Tyrosine Kinase Inhibitor Pazopanib Inhibits Platelet Procoagulant Activity in Renal Cell Carcinoma Patients. Frontiers in Cardiovascular Medicine, 5, Article 142. https://doi.org/10.3389/fcvm.2018.00142

Gillissen, A., van den Akker, T., Caram-Deelder, C., Henriquez, D. D. C. A., Bloemenkamp, K. W. M., van Roosmalen, J. J. M., Eikenboom, J., van der Bom, J. G., Henskens, Y., Scheepers, L., & TeMpOH-1 study group (2018). Association between fluid management and dilutional coagulopathy in severe postpartum haemorrhage: a nationwide retrospective cohort study. BMC Pregnancy and Childbirth, 18(1), Article 398. https://doi.org/10.1186/s12884-018-2021-9

Zhou, T. L., Henry, R. M. A., Stehouwer, C. D. A., van Sloten, T. T., Reesink, K. D., & Kroon, A. A. (2018). Blood Pressure Variability, Arterial Stiffness, and Arterial Remodeling: The Maastricht Study. Hypertension, 72(4), 1002-1010. https://doi.org/10.1161/HYPERTENSIONAHA.118.11325

ten Cate, H., Lensing, A. W. A., Weitz, J. I., Middeldorp, S., Beyer-Westendorf, J., Kubitza, D., Brighton, T., Raskob, G. E., Mismetti, P., Prandoni, P., Gebel, M., & Prins, M. H. (2018). The prothrombin time does not predict the risk of recurrent venous thromboembolism or major bleeding in rivaroxaban-treated patients. Thrombosis Research, 170, 75-83. https://doi.org/10.1016/j.thromres.2018.08.008

Vries, M. J., van der Meijden, P. E., Kuiper, G. J., Nelemans, P. J., Wetzels, R. J., van Oerle, R. G., Lance, M. D., ten Cate, H., & Henskens, Y. M. (2018). Preoperative screening for bleeding disorders: A comprehensive laboratory assessment of clinical practice. Research and practice in thrombosis and haemostasis, 2(4), 767-777. https://doi.org/10.1002/rth2.12114

Peeters, F. E. C. M., Dudink, E. A. M. P., Kimenai, D. M., Weijs, B., Altintas, S., Heckman, L. I. B., Mihl, C., Schurgers, L. J., Wildberger, J. E., Meex, S. J. R., Kietselaer, B. L. J. H., & Crijns, H. J. G. M. (2018). Vitamin K Antagonists, Non-Vitamin K Antagonist Oral Anticoagulants, and Vascular Calcification in Patients with Atrial Fibrillation. TH open : companion journal to thrombosis and haemostasis, 2(4), e391-e398. https://doi.org/10.1055/s-0038-1675578

Hofmann, I., Geer, M. J., Vogtle, T., Crispin, A., Campagna, D. R., Barr, A., Calicchio, M. L., Heising, S., van Geffen, J. P., Kuijpers, M. J. E., Heemskerk, J. W. M., Eble, J. A., Schmitz-Abe, K., Obeng, E. A., Douglas, M., Freson, K., Pondarre, C., Favier, R., Jarvis, G. E., ... Senis, Y. A. (2018). Congenital macrothrombocytopenia with focal myelofibrosis due to mutations in human G6b-B is rescued in humanized mice. Blood, 132(13), 1399-1412. https://doi.org/10.1182/blood-2017-08-802769

Geer, M. J., van Geffen, J. P., Gopalasingam, P., Vogtle, T., Smith, C. W., Heising, S., Kuijpers, M. J. E., Tullemans, B. M. E., Jarvis, G. E., Eble, J. A., Jeeves, M., Overduin, M., Heemskerk, J. W. M., Mazharian, A., & Senis, Y. A. (2018). Uncoupling ITIM receptor G6b-B from tyrosine phosphatases Shp1 and Shp2 disrupts murine platelet homeostasis. Blood, 132(13), 1413-1425. https://doi.org/10.1182/blood-2017-10-802975

Zwaveling, S., Bloemen, S., de Laat, B., Ten Cate, H., & Ten Cate-Hoek, A. (2018). Calibrated Automated Thrombinography (CAT), a Tool to Identify Patients at Risk of Bleeding during Anticoagulant Therapy: A Systematic Review. TH open : companion journal to thrombosis and haemostasis, 2(3), 291-302. https://doi.org/10.1055/s-0038-1672183

Baaten, C. C. F. M. J., Swieringa, F., Misztal, T., Mastenbroek, T. G., Feijge, M. A. H., Bock, P. E., Donners, M. M. P. C., Collins, P. W., Li, R., van der Meijden, P. E. J., & Heemskerk, J. W. M. (2018). Platelet heterogeneity in activation-induced glycoprotein shedding: functional effects. Blood advances, 2(18), 2320-2331. https://doi.org/10.1182/bloodadvances.2017011544

Koenen, R. R., & Aikawa, E. (2018). Editorial: Extracellular Vesicle-Mediated Processes in Cardiovascular Diseases. Frontiers in Cardiovascular Medicine, 5, Article 133. https://doi.org/10.3389/fcvm.2018.00133

Richelle, G. J. J., Schmidt, M., Ippel, H., Hackeng, T. M., van Maarseveen, J. H., Nuijens, T., & Timmerman, P. (2018). A One-Pot "Triple-C" Multicyclization Methodology for the Synthesis of Highly Constrained Isomerically Pure Tetracyclic Peptides. Chembiochem, 19(18), 1934-1938. https://doi.org/10.1002/cbic.201800346

Smulders, M. W., Bekkers, S. C. A. M., van Cauteren, Y. J. M., Liefhebber, A., Vermeer, J. R., Vervuurt, J., van Dieijen-Visser, M. P., Mingels, A. M. A., Rocca, H.-P. B.-L., Dagnelie, P. C., Wildberger, J. E., Crijns, H. J. G. M., & Kietselaer, B. L. J. H. (2018). Risk stratification and role for additional diagnostic testing in patients with acute chest pain and normal high-sensitivity cardiac troponin levels. PLOS ONE, 13(9), Article e0203506. https://doi.org/10.1371/journal.pone.0203506

van der Linden, N., Wildi, K., Twerenbold, R., Pickering, J. W., Than, M., Cullen, L., Greenslade, J., Parsonage, W., Nestelberger, T., Boeddinghaus, J., Badertscher, P., Gimenez, M., Klinkenberg, L. J. J., Bekers, O., Schoni, A., Keller, D. I., Sabti, Z., Puelacher, C., Cupa, J., ... Mueller, C. (2018). Combining High-Sensitivity Cardiac Troponin I and Cardiac Troponin T in the Early Diagnosis of Acute Myocardial Infarction. Circulation, 138(10), 989-999. https://doi.org/10.1161/CIRCULATIONAHA.117.032003

Eggebrecht, L., Prochaska, J. H., Schulz, A., Arnold, N., Juenger, C., Goebel, S., Laubert-Reh, D., Binder, H., Beutel, M. E., Pfeiffer, N., Blankenberg, S., Lackner, K. J., Spronk, H. M., ten Cate, H., Muenzel, T., & Wild, P. S. (2018). Intake of Vitamin K Antagonists and Worsening of Cardiac and Vascular Disease: Results From the Population-Based Gutenberg Health Study. Journal of the American Heart Association, 7(17), Article 008650. https://doi.org/10.1161/JAHA.118.008650

Henskens, Y., & NIHR BioResource - Rare Diseases (2018). Publisher Correction: Telomerecat: A ploidy-agnostic method for estimating telomere length from whole genome sequencing data. Scientific Reports, 8(1), Article 13376. https://doi.org/10.1038/s41598-018-31524-0

Tullemans, B. M. E., Heemskerk, J. W. M., & Kuijpers, M. J. E. (2018). Acquired platelet antagonism: off-target antiplatelet effects of malignancy treatment with tyrosine kinase inhibitors. Journal of Thrombosis and Haemostasis, 16(9), 1686-1699. https://doi.org/10.1111/jth.14225

Stifft, F., van Kuijk, S. M. J., Bekers, O., & Christiaans, M. H. L. (2018). Increase in tacrolimus exposure after steroid tapering is influenced by CYP3A5 and pregnane X receptor genetic polymorphisms in renal transplant recipients. Nephrology Dialysis Transplantation, 33(9), 1668-1675. https://doi.org/10.1093/ndt/gfy096

ten Cate, H. (2018). Testing direct oral anticoagulants: embedding in structured long-term care. Blood Transfusion, 16(5), 410-412. https://doi.org/10.2450/2017.0197-17

Geijselaers, S. L. C., Sep, S. J. S., Schram, M. T., van Boxtel, M. P. J., van Sloten, T. T., Roodt, J. O. H., Henry, R. M. A., Reesink, K. D., Schaper, N. C., Dagnelie, P. C., van der Kallen, C. J. H., Biessels, G. J., & Stehouwer, C. D. A. (2018). Carotid circumferential wall stress is not associated with cognitive performance among individuals in late middle age: The Maastricht Study. Atherosclerosis, 276, 15-22. https://doi.org/10.1016/j.atherosclerosis.2018.07.003

Baaten, C. C. F. M. J., Moenen, F. C. J. I., Henskens, Y. M. C., Swieringa, F., Wetzels, R. J. H., van Oerle, R., Heijnen, H. F. G., ten Cate, H., Holloway, G. P., Beckers, E. A. M., Heemskerk, J. W. M., & van der Meijden, P. E. J. (2018). Impaired mitochondrial activity explains platelet dysfunction in thrombocytopenic cancer patients undergoing chemotherapy. Haematologica-the Hematology Journal, 103(9), 1557-1567. https://doi.org/10.3324/haematol.2017.185165

Dickhout, A., & Koenen, R. R. (2018). Extracellular Vesicles as Biomarkers in Cardiovascular Disease; Chances and Risks. Frontiers in Cardiovascular Medicine, 5, Article 113. https://doi.org/10.3389/fcvm.2018.00113

Schelpe, A.-S., Orlando, C., Ercig, B., Geeroms, C., Pareyn, I., Vandeputte, N., Pereira, L. C., Roose, E., Fostier, K., Nicolaes, G. A. F., Deckmyn, H., De Meyer, S. F., Vanhoorelbeke, K., & Jochmans, K. (2018). Child-onset thrombotic thrombocytopenic purpura caused by p.R498C and p.G259PfsX133 mutations in ADAMTS13. European Journal of Haematology, 101(2), 191-199. https://doi.org/10.1111/ejh.13094

Amin, E. E., Joore, M. A., ten Cate, H., Meijer, K., Tick, L. W., Middeldorp, S., Mostard, G. J. M., ten Wolde, M., Van den Heiligenberg, S. M., Van Wissen, S., Van de Poel, M. H. W., Villalta, S., Serne, E. H., Otten, H.-M., Klappe, E. H., Prandoni, P., & ten Cate-Hoek, A. J. (2018). Clinical and economic impact of compression in the acute phase of deep vein thrombosis. Journal of Thrombosis and Haemostasis, 16(8), 1555-1563. https://doi.org/10.1111/jth.14163

Crombag, G. A. J. C., Spronk, H. M., Nelemans, P., Schreuder, F. H. B. M., Truijman, M. T. B., van Dijk, A. C., de Rotte, A. A. J., Liem, M. I., Daemen, M. J. A. P., van der Steen, A. F. W., Mess, W. H., Nederkoorn, P. J., Hendrikse, J., van der Lugt, A., Wildberger, J. E., ten Cate, H., van Oostenbrugge, R. J., & Kooi, M. E. (2018). No Association between Thrombin Generation and Intra-Plaque Haemorrhage in Symptomatic Carotid Atherosclerotic Plaques: The Plaque at RISK (PARISK) Study. Thrombosis and Haemostasis, 118(8), 1461-1469. https://doi.org/10.1055/s-0038-1666858

Kremers, B. M. M., Ten Cate, H., & Spronk, H. M. H. (2018). Pleiotropic effects of the hemostatic system. Journal of Thrombosis and Haemostasis, 16(8), 1464-1473. https://doi.org/10.1111/jth.14161

Brinkhues, S., Dukers-Muijrers, N. H. T. M., Hoebe, C. J. P. A., van der Kallen, C. J. H., Koster, A., Henry, R. M. A., Stehouwer, C. D. A., Savelkoul, P. H. M., Schaper, N. C., & Schram, M. T. (2018). Social Network Characteristics Are Associated With Type 2 Diabetes Complications: The Maastricht Study. Diabetes Care, 41(8), 1654-1662. https://doi.org/10.2337/dc17-2144

Witten, A., Bolbrinker, J., Barysenka, A., Huber, M., Ruhle, F., Nowak-Gottl, U., Garbe, E., Kreutz, R., & Stoll, M. (2018). Targeted resequencing of a locus for heparin-induced thrombocytopenia on chromosome 5 identified in a genome-wide association study. Journal of Molecular Medicine, 96(8), 765-775. https://doi.org/10.1007/s00109-018-1661-6

D'Alessandro, E., Posma, J. J. N., Spronk, H. M. H., & ten Cate, H. (2018). Tissue factor (:Factor VIIa) in the heart and vasculature: More than an envelope. Thrombosis Research, 168, 130-137. https://doi.org/10.1016/j.thromres.2018.06.020

Veugen, M. G. J., Henry, R. M. A., Brunner-La Rocca, H.-P., Dagnelie, P. C., Schram, M. T., van Agtmaal, M. J. M., van der Kallen, C. J. H., Sep, S. J. S., van Boxtel, M. P. J., Bekers, O., Meex, S. J. R., Jansen, J. F. A., Kroon, A. A., & Stehouwer, C. D. A. (2018). Cross-sectional associations between cardiac biomarkers, cognitive performance, and structural brain changes are modified by age: The Maastricht Study. Arteriosclerosis Thrombosis and Vascular Biology, 38(8), 1948-1958. https://doi.org/10.1161/ATVBAHA.118.311082

van Setten, J., Brody, J. A., Jamshidi, Y., Swenson, B. R., Butler, A. M., Campbell, H., Del Greco, F. M., Evans, D. S., Gibson, Q., Gudbjartsson, D. F., Kerr, K. F., Krijthe, B. P., Lyytikainen, L.-P., Muller, C., Muller-Nurasyid, M., Nolte, I. M., Padmanabhan, S., Ritchie, M. D., Robino, A., ... Sotoodehnia, N. (2018). PR interval genome-wide association meta-analysis identifies 50 loci associated with atrial and atrioventricular electrical activity. Nature Communications, 9(1), Article 2904. https://doi.org/10.1038/s41467-018-04766-9

Peeters, F. E. C. M., Meex, S. J. R., Dweck, M. R., Aikawa, E., Crijns, H. J. G. M., Schurgers, L. J., & Kietselaer, B. L. J. H. (2018). Calcific aortic valve stenosis: hard disease in the heart. European Heart Journal, 39(28), 2618–2624. https://doi.org/10.1093/eurheartj/ehx653

Vroemen, W. H. M., de Boer, D., Streng, A. S., Mingels, A. M. A., & Meex, S. J. R. (2018). Elevated Cardiac Troponin T in Skeletal Myopathies: Skeletal TnT Cross-Reactivity and/or Cardiac TnT Expression?Journal of the American College of Cardiology, 72(3), 347-349. https://doi.org/10.1016/j.jacc.2018.05.017

Prins, B. P., Mead, T. J., Brody, J. A., Sveinbjornsson, G., Ntalla, I., Bihlmeyer, N. A., van den Berg, M., Bork-Jensen, J., Cappellani, S., Van Duijvenboden, S., Klena, N. T., Gabriel, G. C., Liu, X., Gulec, C., Grarup, N., Haessler, J., Hall, L. M., Iorio, A., Isaacs, A., ... Jamshidi, Y. (2018). Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6. Genome Biology, 19(1), Article 87. https://doi.org/10.1186/s13059-018-1457-6

Vajen, T., Koenen, R. R., Werner, I., Staudt, M., Projahn, D., Curaj, A., Sonmez, T. T., Simsekyilmaz, S., Schumacher, D., Mollmann, J., Hackeng, T. M., von Hundelshausen, P., Weber, C., & Liehn, E. A. (2018). Blocking CCL5-CXCL4 heteromerization preserves heart function after myocardial infarction by attenuating leukocyte recruitment and NETosis. Scientific Reports, 8(1), Article 10647. https://doi.org/10.1038/s41598-018-29026-0

Whitworth, J., Smith, P. S., Martin, J.-E., West, H., Luchetti, A., Rodger, F., Clark, G., Carss, K., Stephens, J., Stirrups, K., Penkett, C., Mapeta, R., Ashford, S., Megy, K., Shakeel, H., Ahmed, M., Adlard, J., Barwell, J., Brewer, C., ... NIHR BioResource Rare Diseases Consortium (2018). Comprehensive Cancer-Predisposition Gene Testing in an Adult Multiple Primary Tumor Series Shows a Broad Range of Deleterious Variants and Atypical Tumor Phenotypes. American Journal of Human Genetics, 103(1), 3-18. https://doi.org/10.1016/j.ajhg.2018.04.013

Ito, Y., Carss, K. J., Duarte, S. T., Hartley, T., Keren, B., Kurian, M. A., Marey, I., Charles, P., Mendonca, C., Nava, C., Pfundt, R., Sanchis-Juan, A., van Bokhoven, H., van Essen, A., van Ravenswaaij-Arts, C., Boycott, K. M., Kernohan, K. D., Dyack, S., Raymond, F. L., ... Care4Rare Canada Consortium (2018). De Novo Truncating Mutations in WASF1 Cause Intellectual Disability with Seizures. American Journal of Human Genetics, 103(1), 144-153. https://doi.org/10.1016/j.ajhg.2018.06.001

Winter, C., Silvestre-Roig, C., Ortega-Gomez, A., Lemnitzer, P., Poelman, H., Schumski, A., Winter, J., Drechsler, M., de Jong, R., Immler, R., Sperandio, M., Hristov, M., Zeller, T., Nicolaes, G. A. F., Weber, C., Viola, J. R., Hidalgo, A., Scheiermann, C., & Soehnlein, O. (2018). Chrono-pharmacological Targeting of the CCL2-CCR2 Axis Ameliorates Atherosclerosis. Cell Metabolism, 28(1), 175-182.e5. https://doi.org/10.1016/j.cmet.2018.05.002

Amin, E. E., van Kuijk, S. M. J., Joore, M. A., Prandoni, P., ten Cate, H., & ten Cate-Hoek, A. J. (2018). Development and Validation of a Practical Two-Step Prediction Model and Clinical Risk Score for Post-Thrombotic Syndrome. Thrombosis and Haemostasis, 118(7), 1242-1249. https://doi.org/10.1055/s-0038-1655743

van Doorn, P., Rosing, J., Duckers, C., Hackeng, T. M., Simioni, P., & Castoldi, E. (2018). Factor V Has Anticoagulant Activity in Plasma in the Presence of TFPI: Difference between FV1 and FV2. Thrombosis and Haemostasis, 118(7), 1194-1202. https://doi.org/10.1055/s-0038-1656549

Moenen, F. C. J. I., Nelemans, P. J., Schols, S. E. M., Schouten, H. C., Henskens, Y. M. C., & Beckers, E. A. M. (2018). The diagnostic accuracy of bleeding assessment tools for the identification of patients with mild bleeding disorders: A systematic review. Haemophilia, 24(4), 525-535. https://doi.org/10.1111/hae.13486

Swieringa, F., Spronk, H. M. H., Heemskerk, J. W. M., & van der Meijden, P. E. J. (2018). Integrating platelet and coagulation activation in fibrin clot formation. Research and practice in thrombosis and haemostasis, 2(3), 450-460. https://doi.org/10.1002/rth2.12107

Kimenai, D. M., Janssen, E. B. N. J., Eggers, K. M., Lindahl, B., den Ruijter, H. M., Bekers, O., Appelman, Y., & Meex, S. J. R. (2018). Sex-Specific Versus Overall Clinical Decision Limits for Cardiac Troponin I and T for the Diagnosis of Acute Myocardial Infarction: A Systematic Review. Clinical Chemistry, 64(7), 1034-1043. https://doi.org/10.1373/clinchem.2018.286781

Vaidya, A., Kleinegris, M.-C., Severens, J. L., Ramaekers, B. L., ten Cate-Hoek, A. J., ten Cate, H., & Joore, M. A. (2018). Comparison of EQ-5D and SF-36 in untreated patients with symptoms of intermittent claudication. Journal of Comparative Effectiveness Research, 7(6), 535-548. https://doi.org/10.2217/cer-2017-0029

van Bussel, B. C. T., Henry, R. M. A., Schalkwijk, C. G., Dekker, J. M., Nijpels, G., Feskens, E. J. M., & Stehouwer, C. D. A. (2018). Alcohol and red wine consumption, but not fruit, vegetables, fish or dairy products, are associated with less endothelial dysfunction and less low-grade inflammation: the Hoorn Study. European Journal of Nutrition, 57(4), 1409-1419. https://doi.org/10.1007/s00394-017-1420-4

Panova-Noeva, M., Schulz, A., Spronk, H. M., Beicht, A., Laubert-Reh, D., van Oerle, R., Arnold, N., Prochaska, J. H., Blettner, M., Beutel, M., Pfeiffer, N., Munzel, T., Lackner, K. J., ten Cate, H., & Wild, P. S. (2018). Clinical Determinants of Thrombin Generation Measured in Presence and Absence of Platelets-Results from the Gutenberg Health Study. Thrombosis and Haemostasis, 118(5), 873-882. https://doi.org/10.1055/s-0038-1641565

Lin, H., van Setten, J., Smith, A. V., Bihlmeyer, N. A., Warren, H. R., Brody, J. A., Radmanesh, F., Hall, L., Grarup, N., Muller-Nurasyid, M., Boutin, T., Verweij, N., Lin, H. J., Li-Gao, R., van den Berg, M. E., Marten, J., Weiss, S., Prins, B. P., Haessler, J., ... Isaacs, A. (2018). Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval. Circulation: Genomic and Precision Medicine, 11(5), Article e002037 . https://doi.org/10.1161/CIRCGEN.117.002037

ten Cate, H., Olie, R. H., ten Cate-Hoek, A. J., & Henskens, Y. M. C. (2018). Direct oral anticoagulants: When to consider laboratory testing?International Journal of Laboratory Hematology, 40(S1), 30-33. https://doi.org/10.1111/ijlh.12816

De Maertelaere, E., Castoldi, E., Van Haute, I., Deeren, D., & Devreese, K. M. (2018). The interaction of factor V and tissue factor pathway inhibitor in a myeloma patient with acquired factor V deficiency. Haemophilia, 24(3), E160-E163. https://doi.org/10.1111/hae.13492