• 2012
    • Gladka, M. M., Martins, P. A. D. C., & de Windt, L. J. (2012). Small changes can make a big difference - MicroRNA regulation of cardiac hypertrophy. Journal of Molecular and Cellular Cardiology, 52(1), 74-82. https://doi.org/10.1016/j.yjmcc.2011.09.015
    • ter Horst, P., Smits, J. F. M., & Blankesteijn, W. M. (2012). The Wnt/Frizzled pathway as a therapeutic target for cardiac hypertrophy: where do we stand. Acta Physiologica, 204(1), 110-117. https://doi.org/10.1111/j.1748-1716.2011.02309.x
    • Halbach, N. S. J., Smeets, E. E. J., Bierau, J., Keularts, I. M. L. W., Plasqui, G., Julu, P. O. O., Engerström, I. W., Bakker, J. A., & Curfs, L. M. G. (2012). Altered carbon dioxide metabolism and creatine abnormalities in rett syndrome. JIMD reports, 3, 117-24. https://doi.org/10.1007/8904_2011_76
  • 2011
    • Nabben, M., Hoeks, J., Kornips, C. F. P., Van Beurden, D., Briedé, J. J., Hesselink, M. K. C., Glatz, J. F., & Schrauwen, P. (2011). Significance of uncoupling protein 3 in mitochondrial function upon mid- and long-term dietary high-fat exposure. Febs Letters, 585(24), 4010-4017. https://doi.org/10.1016/j.febslet.2011.11.012
    • Bartelds, B., Borgdorff, M. A., Smit-van Oosten, A., Takens, J., Boersma, B., Nederhoff, M. G., Elzenga, N. J., van Gilst, W. H., De Windt, L. J., & Berger, R. M. F. (2011). Differential responses of the right ventricle to abnormal loading conditions in mice: pressure vs. volume load. European journal of heart failure, 13(12), 1275-1282. https://doi.org/10.1093/eurjhf/hfr134
    • He, B. J., Joiner, M. A., Singh, M. V., Luczak, E. D., Swaminathan, P. D., Koval, O. M., Kutschke, W., Allamargot, C., Yang, J., Guan, X., Zimmerman, K., Grumbach, I. M., Weiss, R. M., Spitz, D. R., Sigmund, C. D., Blankesteijn, W. M., Heymans, S., Mohler, P. J., & Anderson, M. E. (2011). Oxidation of CaMKII determines the cardiotoxic effects of aldosterone. Nature Medicine, 17(12), 1610-U125. https://doi.org/10.1038/nm.2506
    • Al-Roubaie, S., Jahnsen, E. D., Mohammed, M., Henderson-Toth, C., & Jones, E. A. V. (2011). Rheology of embryonic avian blood. American Journal of Physiology-heart and Circulatory Physiology, 301(6), H2473-81. https://doi.org/10.1152/ajpheart.00475.2011
    • Jones, E. A. V. (2011). The initiation of blood flow and flow induced events in early vascular development. Seminars in Cell & Developmental Biology, 22(9), 1028-35. https://doi.org/10.1016/j.semcdb.2011.09.020
    • Armand, A.-S., Laziz, I., Djeghloul, D., Lecolle, S., Bertrand, A. T., Biondi, O., De Windt, L. J., & Chanoine, C. (2011). Apoptosis-Inducing Factor Regulates Skeletal Muscle Progenitor Cell Number and Muscle Phenotype. PLOS ONE, 6(11), 15. https://doi.org/10.1371/journal.pone.0027283
    • Laeremans, H., Hackeng, T. M., van Zandvoort, M. A. M. J., Thijssen, V. L. J. L., Janssen, B. J. A., Ottenheijm, H. C. J., Smits, J. F. M., & Blankesteijn, W. M. (2011). Blocking of Frizzled Signaling With a Homologous Peptide Fragment of Wnt3a/Wnt5a Reduces Infarct Expansion and Prevents the Development of Heart Failure After Myocardial Infarction. Circulation, 124(15), 1626-U107. https://doi.org/10.1161/CIRCULATIONAHA.110.976969
    • van Almen, G. C., Verhesen, W., van Leeuwen, R. E. W., van de Vrie, M., Eurlings, C., Schellings, M. W. M., Swinnen, M., Cleutjens, J. P. M., van Zandvoort, M. A. M. J., Heymans, S., & Schroen, B. (2011). MicroRNA-18 and microRNA-19 regulate CTGF and TSP-1 expression in age-related heart failure. Aging Cell, 10(5), 769-779. https://doi.org/10.1111/j.1474-9726.2011.00714.x
    • van Almen, G. C., Swinnen, M., Carai, P., Verhesen, W., Cleutjens, J. P. M., D'hooge, J., Verheyen, F. K., Pinto, Y. M., Schroen, B., Carmeliet, P., & Heymans, S. (2011). Absence of thrombospondin-2 increases cardiomyocyte damage and matrix disruption in doxorubicin-induced cardiomyopathy. Journal of Molecular and Cellular Cardiology, 51(3), 318-328. https://doi.org/10.1016/j.yjmcc.2011.05.010
    • Jones, E. A. V. (2011). Mechanical factors in the development of the vascular bed. Respiratory physiology & neurobiology, 178(1), 59-65. https://doi.org/10.1016/j.resp.2011.03.026
    • Olieslagers, S., Pardali, E., Tchaikovski, V., ten Dijke, P., & Waltenberger, J. (2011). TGF-beta 1/ALK5-induced monocyte migration involves PI3K and p38 pathways and is not negatively affected by diabetes mellitus. Cardiovascular Research, 91(3), 510-518. https://doi.org/10.1093/cvr/cvr100
    • Verkaar, F., van der Stelt, M., Blankesteijn, W. M., van der Doelen, A. A., & Zaman, G. J. R. (2011). Discovery of Novel Small Molecule Activators of beta-Catenin Signaling. PLOS ONE, 6(4), 7. https://doi.org/10.1371/journal.pone.0019185
    • Verkaar, F., van der Doelen, A. A., Smits, J. F. M., Blankesteijn, W. M., & Zaman, G. J. R. (2011). Inhibition of Wnt/beta-Catenin Signaling by p38 MAP Kinase Inhibitors Is Explained by Cross-Reactivity with Casein Kinase I delta/epsilon. Chemistry & Biology, 18(4), 485-494. https://doi.org/10.1016/j.chembiol.2011.01.015
    • el Azzouzi, H., Leptidis, S., Bourajjaj, M., Armand, A.-S., van der Nagel, R., van Bilsen, M., Martins, P. A. D. C., & De Windt, L. J. (2011). Peroxisome Proliferator-activated Receptor (PPAR) Gene Profiling Uncovers Insulin-like Growth Factor-1 as a PPAR alpha Target Gene in Cardioprotection. Journal of Biological Chemistry, 286(16), 14598-14607. https://doi.org/10.1074/jbc.M111.220525
    • Perino, A., Ghigo, A., Ferrero, E., More, F., Santulli, G., Baillie, G. S., Damilano, F., Dunlop, A. J., Pawson, C., Walser, R., Levi, R., Altruda, F., Silengo, L., Langeberg, L. K., Neubauer, G., Heymans, S., Lembo, G., Wymann, M. P., Wetzker, R., ... Hirsch, E. (2011). Integrating Cardiac PIP3 and cAMP Signaling through a PKA Anchoring Function of p110 gamma. Molecular Cell, 42(1), 84-95. https://doi.org/10.1016/j.molcel.2011.01.030
    • Mischke, K., Knackstedt, C., Fache, K., Reith, S., Rana, O., Saygili, E., Gemein, C., Becker, M., Marx, N., & Schauerte, P. (2011). Electrical remodelling in cardiac resynchronization therapy: decrease in intrinsic QRS duration. Acta Cardiologica, 66(2), 175-180. https://doi.org/10.1080/AC.66.2.2071248
    • Muzzarelli, S., Stricker, B. H., Pfister, O., Foglia, P., Moschovitis, G., Mombelli, G., & Brunner-La Rocca, H. (2011). Individual dosage of digoxin in patients with heart failure. QJM: An International Journal of Medicine, 104(4), 309-317. https://doi.org/10.1093/qjmed/hcq196
    • van de Vrie, M., Heymans, S., & Schroen, B. (2011). MicroRNA Involvement in Immune Activation During Heart Failure. Cardiovascular Drugs and Therapy, 25(2), 161-170. https://doi.org/10.1007/s10557-011-6291-y
    • Czepluch, F. S., Olieslagers, S., van Hulten, R., Voo, S. A., & Waltenberger, J. (2011). VEGF-A-induced chemotaxis of CD16+monocytes is decreased secondary to lower VEGFR-1 expression. Atherosclerosis, 215(2), 331-338. https://doi.org/10.1016/j.atherosclerosis.2011.01.004
    • Leventhal, M. E., Denhaerynck, K., Brunner-La Rocca, H.-P., Burnand, B., Conca, A., Bernasconi, A. T., Mahrer-Imhof, R., Froelicher, E. S., & De Geest, S. (2011). Swiss Interdisciplinary Management Programme for Heart Failure (SWIM-HF). Swiss Medical Weekly, 141, 10. https://doi.org/10.4414/smw.2011.13171
    • Bläuer, C., Mahrer-Imhof, R., Brunner-La Rocca, H., Mueller, C. P., Eze, G., Milbich, I., & Spirig, R. (2011). Development and Implementation of a multidisciplinary nurse-led educational programme for inpatients with heart failure: The Basel-HF-Programme: Entwicklung und Implementierung eines multidisziplinären pflegegeleiteten Programms zur stationären Betreuung von Patientinnen und Patienten mit Herzinsuffizienz: Das Basler HI-Programm. Pflege, 24(1), 29-41. https://doi.org/10.1024/1012-5302/a000089
    • Nabben, M., Shabalina, I. G., Kornips, C. F. P., Van Beurden, D., Cannon, B., Schrauwen, P., Nedergaard, J., & Hoeks, J. (2011). Uncoupled respiration, ROS production, acute lipotoxicity and oxidative damage in isolated skeletal muscle mitochondria from UCP3-ablated mice.Biochimica et Biophysica Acta-bioenergetics, 1807(9), 1095-1105. https://doi.org/10.1016/j.bbabio.2011.04.003
    • Eschenhagen, T., Force, T., Ewer, M. S., De Keulenaer, G. W., Suter, T. M., Anker, S. D., Avkiran, M., de Azambuja, E., Balligand, J. L., Brutsaert, D. L., Condorelli, G., Hansen, A., Heymans, S., Hill, J. A., Hirsch, E., Hilfiker-Kleiner, D., Janssens, S., de Jong, S., Neubauer, G., ... Shah, A. M. (2011). Cardiovascular side effects of cancer therapies: a position statement from the Heart Failure Association of the European Society of Cardiology. European journal of heart failure, 13(1), 1-10. https://doi.org/10.1093/eurjhf/hfq213
    • Czepluch, F. S., Barres, R., Caidahl, K., Olieslagers, S., Krook, A., Rickenlund, A., Zierath, J. R., & Waltenberger, J. (2011). Strenuous physical exercise adversely affects monocyte chemotaxis. Thrombosis and Haemostasis, 105(1), 122-130. https://doi.org/10.1160/TH10-06-0363
    • Alzand, B. S. N., Mihl, C., & La Rocca, H. P. B. (2011). Dehydration with High Natriuretic Peptide Levels! A Word of Caution. Cardiology, 118(2), 75-78. https://doi.org/10.1159/000326855
  • 2010
    • Rother, M., Krohn, S., Kania, G., Vanhoutte, D., Eisenreich, A., Wang, X., Westermann, D., Savvatis, K., Dannemann, N., Skurk, C., Hilfiker-Kleiner, D., Cathomen, T., Fechner, H., Rauch, U., Schultheiss, H.-P., Heymans, S., Eriksson, U., Scheibenbogen, C., & Poller, W. (2010). Matricellular Signaling Molecule CCN1 Attenuates Experimental Autoimmune Myocarditis by Acting as a Novel Immune Cell Migration Modulator. Circulation, 122(25), 2688-2698. https://doi.org/10.1161/CIRCULATIONAHA.110.945261
    • Kaiser, C. A., Galatius, S., Erne, P., Eberli, F., Alber, H., Rickli, H., Pedrazzini, G., Hornig, B., Bertel, O., Bonetti, P., De Servi, S., Brunner-La Rocca, H.-P., Ricard, I., & Pfisterer, M. E. (2010). Drug-Eluting versus Bare-Metal Stents in Large Coronary Arteries. New England Journal of Medicine, 363(24), 2310-2319. https://doi.org/10.1056/NEJMoa1009406
    • Martins, P. A. D. C., Salic, K., Gladka, M. M., Armand, A.-S., Leptidis, S., el Azzouzit, H., Hansen, A., Coenen-de Roo, C. J., Bierhuizen, M. F. A., van der Nagel, R., van Kuik, J., de Weger, R. A., de Bruin, A., Condorelli, G., Arbones, M. L., Eschenhagen, T., & De Windt, L. J. (2010). MicroRNA-199b targets the nuclear kinase Dyrk1a in an auto-amplification loop promoting calcineurin/NFAT signalling. Nature Cell Biology, 12(12), 1220-U231. https://doi.org/10.1038/ncb2126
    • Donners, M. P. C., Wolfs, I. M. J., Olieslagers, S., Mohammadi-Motahhari, Z., Tchaikovski, V., Heeneman, S., van Buul, J. D., Caolo, V., Molin, D. G. M., Post, M. J., & Waltenberger, J. (2010). A Disintegrin and Metalloprotease 10 Is a Novel Mediator of Vascular Endothelial Growth Factor: Induced Endothelial Cell Function in Angiogenesis and Is Associated With Atherosclerosis. Arteriosclerosis Thrombosis and Vascular Biology, 30(11), 2188-U382. https://doi.org/10.1161/ATVBAHA.110.213124
    • van den Berg, S. A., Nabben, M., Bijland, S., Voshol, P. J., van Klinken, J. B., Havekes, L. M., Romijn, H. A., Hoeks, J., Hesselink, M. K., Schrauwen, P., & van Dijk, K. W. (2010). High levels of whole-body energy expenditure are associated with a lower coupling of skeletal muscle mitochondria in C57B1/6 mice. Metabolism-Clinical and Experimental, 59(11), 1612-1618. https://doi.org/10.1016/j.metabol.2010.03.008
    • den Hengst, W. A., Gielis, J. F., Lin, J. Y., Van Schil, P. E. Y., De Windt, L. J., & Moens, A. L. (2010). Lung ischemia-reperfusion injury: a molecular and clinical view on a complex pathophysiological process. American Journal of Physiology-heart and Circulatory Physiology, 299(5), H1283-H1299. https://doi.org/10.1152/ajpheart.00251.2010
    • Maeder, M. T., Thompson, B. R., Brunner-La Rocca, H.-P., & Kaye, D. M. (2010). Hemodynamic Basis of Exercise Limitation in Patients With Heart Failure and Normal Ejection Fraction. Journal of the American College of Cardiology, 56(11), 855-863. https://doi.org/10.1016/j.jacc.2010.04.040
    • Leenders, J. J., Wijnen, W. J., Hiller, M., van der Made, I., Lentink, V., van Leeuwen, R. E. W., Herias, V., Pokharel, S., Heymans, S., de Windt, L. J., Hoydal, M. A., Pinto, Y. M., & Creemers, E. E. (2010). Regulation of Cardiac Gene Expression by KLF15, a Repressor of Myocardin Activity. Journal of Biological Chemistry, 285(35), 27449-27456. https://doi.org/10.1074/jbc.M110.107292
    • Laeremans, H., Rensen, S. S. M., Ottenheijm, H. C. J., Smits, J. F. M., & Blankesteijn, W. M. (2010). Wnt/frizzled signalling modulates the migration and differentiation of immortalized cardiac fibroblasts. Cardiovascular Research, 87(3), 514-523. https://doi.org/10.1093/cvr/cvq067
    • Martins, P. A. D. C., Leptidis, S., Salic, K., & De Windt, L. J. (2010). MicroRNA Regulation in Cardiovascular Disease. Current Drug Targets, 11(8), 900-906. https://doi.org/10.2174/138945010791591322
    • Cosemans, J. M. E. M., Van Kruchten, R., Olieslagers, S., Schurgers, L. J., Verheyen, F. K., Munnix, I. C. A., Waltenberger, J., Angelillo-Scherrer, A., Hoylaerts, M. F., Carmeliet, P., & Heemskerk, J. W. M. (2010). Potentiating role of Gas6 and Tyro3, Axl and Mer (TAM) receptors in human and murine platelet activation and thrombus stabilization. Journal of Thrombosis and Haemostasis, 8(8), 1797-1808. https://doi.org/10.1111/j.1538-7836.2010.03935.x
    • Kuster, G. M., Nietlispach, F., Kiowski, W., Schindler, R., Bernheim, A. M., Schuetz, P., Mueller, B., Morgenthaler, N. G., Rueter, F., Riesen, W., Rickli, H., & Brunner-La Rocca, H. P. (2010). Role of RAS Inhibition in the Regulation of Cu/Zn-SOD in the Cardiac and Peripheral Arterial Beds in Humans. Clinical Pharmacology & Therapeutics, 87(6), 686-692. https://doi.org/10.1038/clpt.2010.36
    • Tijsen, A. J., Creemers, E. E., Moerland, P. D., de Windt, L. J., van der Wal, A. C., Kok, W. E., & Pinto, Y. M. (2010). MiR423-5p As a Circulating Biomarker for Heart Failure. Circulation Research, 106(6), 1035-U63. https://doi.org/10.1161/CIRCRESAHA.110.218297
    • van Oort, R. J., Respress, J. L., Li, N., Reynolds, C., De Almeida, A. C., Skapura, D. G., De Windt, L. J., & Wehrens, X. H. T. (2010). Accelerated Development of Pressure Overload-Induced Cardiac Hypertrophy and Dysfunction in an RyR2-R176Q Knockin Mouse Model. Hypertension, 55(4), 932-938. https://doi.org/10.1161/HYPERTENSIONAHA.109.146449
    • Muzzarelli, S., Brunner-La Rocca, H., Pfister, O., Foglia, P., Moschovitis, G., Mombelli, G., & Stricker, H. (2010). Adherence to the medical regime in patients with heart failure. European journal of heart failure, 12(4), 389-396. https://doi.org/10.1093/eurjhf/hfq015
    • Verkaar, F., Blankesteijn, W. M., Smits, J. F. M., & Zaman, G. J. R. (2010). beta-Galactosidase enzyme fragment complementation for the measurement of Wnt/beta-catenin signaling. Faseb Journal, 24(4), 1205-1217. https://doi.org/10.1096/fj.09-141671
    • McCurdy, S., Baicu, C. F., Heymans, S., & Bradshaw, A. D. (2010). Cardiac extracellular matrix remodeling: Fibrillar collagens and Secreted Protein Acidic and Rich in Cysteine (SPARC). Journal of Molecular and Cellular Cardiology, 48(3), 544-549. https://doi.org/10.1016/j.yjmcc.2009.06.018
    • Schalla, S., Bekkers, S. C., Dennert, R., van Suylen, R. J., Waltenberger, J., Leiner, T., Wildberger, J., Crijns, H. J., & Heymans, S. (2010). Replacement and reactive myocardial fibrosis in idiopathic dilated cardiomyopathy: comparison of magnetic resonance imaging with right ventricular biopsy. European journal of heart failure, 12(3), 227-231. https://doi.org/10.1093/eurjhf/hfq004
    • Vanhoutte, D., & Heymans, S. (2010). TIMPs and cardiac remodeling: 'Embracing the MMP-independent-side of the family'. Journal of Molecular and Cellular Cardiology, 48(3), 445-453. https://doi.org/10.1016/j.yjmcc.2009.09.013
    • Kriemler, S., Zahner, L., Schindler, C., Meyer, U., Hartmann, T., Hebestreit, H., Brunner-La Rocca, H. P., van Mechelen, W., & Puder, J. J. (2010). Effect of school based physical activity programme (KISS) on fitness and adiposity in primary schoolchildren: cluster randomised controlled trial. BMJ, 340, 8. https://doi.org/10.1136/bmj.c785