• 2024
    • Santos-Ferreira, D., Diaz, S. O., Ferreira, J. P., Girerd, N., Pellicori, P., Mariottoni, B., Cosmi, F., Hazebroek, M., Verdonschot, J. A. J., Cuthbert, J., Petutschnigg, J., Heymans, S., Staessen, J. A., Pieske, B., Edelmann, F., Clark, A. L., Rossignol, P., Fontes-Carvalho, R., Cleland, J. G. F., & Zannad, F. (2024). Phenotyping patients with ischaemic heart disease at risk of developing heart failure: an analysis of the HOMAGE trial. Esc heart failure, 11(1), 209-218. https://doi.org/10.1002/ehf2.14465
    • Spanò, G., Pehlivanoglu, S., & De Windt, L. J. (2024). Heracles and the Lernaean Hydra: uncovering new layers of transcriptome regulation. Cardiovascular Research, 120(1), 10-12. https://doi.org/10.1093/cvr/cvad192
    • Shanbagh, S., Gadde, S. G., Shetty, R., Heymans, S., Abilash, V. G., Chaurasia, S. S., & Ghosh, A. (2024). Hyperglycemia-induced miR182-5p drives glycolytic and angiogenic response in Proliferative Diabetic Retinopathy and RPE cells via depleting FoxO1. Experimental Eye Research, 238, Article 109713. https://doi.org/10.1016/j.exer.2023.109713
    • Oberman, K., van Leeuwen, B. L., Nabben, M., Villafranca, J. E., & Schoemaker, R. G. (2024). J147 Affects Cognition And Anxiety After Surgery In Zucker Rats. Physiology & Behavior, 273, Article 114413. https://doi.org/10.1016/j.physbeh.2023.114413
    • Neumann, A., Steiner, B., Verket, M., Kanna, N. D. D., Hill, L., McNulty, A., Boyne, J. J. J., Murphy, M., Maaser, Y., Fitzsimons, D., Barrett, M., Ski, C. F., Schuett, K., Helms, T. M., Brunner-La Rocca, H.-P., Zippel-Schultz, B., & PASSION-HF consortium (2024). Patients' expectations and experiences with the usage of a self-care application for heart failure: A qualitative interview study. Digital health, 10, Article 20552076241299649. https://doi.org/10.1177/20552076241299649
    • McDonagh, T. A., Metra, M., Adamo, M., Gardner, R. S., Baumbach, A., Boehm, M., Burri, H., Butler, J., Celutkiene, J., Chioncel, O., Cleland, J. G. F., Crespo-Leiro, M. G., Farmakis, D., Gilard, M., Heymans, S., Hoes, A. W., Jaarsma, T., Jankowska, E. A., Lainscak, M., ... ESC Scientific Document Group (2024). 2023 Focused Update of the 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure. European journal of heart failure, 26(1), 5-17. https://doi.org/10.1002/ejhf.3024
    • Adamo, M., Chioncel, O., Pagnesi, M., Bayes-Genis, A., Abdelhamid, M., Anker, S. D., Antohi, E.-L., Badano, L., Ben Gal, T., Böhm, M., Delgado, V., Dreyfus, J., Faletra, F. F., Farmakis, D., Filippatos, G., Grapsa, J., Gustafsson, F., Hausleiter, J., Jaarsma, T., ... Metra, M. (2024). Epidemiology, Pathophysiology, Diagnosis and Management of Chronic Right-Sided Heart Failure and Tricuspid Regurgitation. A clinical consensus statement of the Heart Failure Association (HFA) and the European Association of Percutaneous Cardiovascular Interventions (EAPCI) of the ESC. European journal of heart failure, 26(1), 18-33. https://doi.org/10.1002/ejhf.3106
    • HENKENS, MICHIEL. T. H. M., RAAFS, ANNE. G., VANLOON, T. I. M., VOS, JACQUELINE. L., VANDENWIJNGAARD, ARTHUR., BRUNNER, HAN. G., KRAPELS, INGRID. P. C., KNACKSTEDT, CHRISTIAN., GERRETSEN, SUZANNE., HAZEBROEK, MARK. R., VERNOOY, KEVIN., NIJVELDT, ROBIN., LUMENS, JOOST., & VERDONSCHOT, JOB. A. J. (2024). Left Atrial Function in Patients with Titin Cardiomyopathy. Journal of Cardiac Failure, 30(1), 51-60. https://doi.org/10.1016/j.cardfail.2023.05.013
    • Litwin, S. E., Komtebedde, J., Seidler, T., Borlaug, B. A., Winkler, S., Solomon, S. D., Eicher, J.-C., Mazimba, S., Khawash, R., Sverdlov, A. L., Hummel, S. L., Bugger, H., Boenner, F., Hoendermis, E., Cikes, M., Demers, C., Silva, G., van Empel, V., Starling, R., ... REDUCE LAP-HF investigators and research staff (2024). Obesity in Heart Failure with Preserved Ejection Fraction: Insights from the REDUCE LAP-HF II Trial. European journal of heart failure, 26(1), 177-189. https://doi.org/10.1002/ejhf.3092
    • Mircheva, A., Vangrieken, P., Al-Nasiry, S., van Schooten, F.-J., Godschalk, R. W. L., & Langie, S. A. S. (2024). Optimizing the Comet Assay-Based In Vitro DNA Repair Assay for Placental Tissue: A Pilot Study with Pre-Eclamptic Patients. International Journal of Molecular Sciences, 25(1), Article 187. https://doi.org/10.3390/ijms25010187
    • Simmonds, S. J., Grootaert, M. O. J., Cuijpers, I., Carai, P., Geuens, N., Herwig, M., Baatsen, P., Hamdani, N., Luttun, A., Heymans, S., & Jones, E. A. V. (2024). Pericyte loss initiates microvascular dysfunction in the development of diastolic dysfunction. European heart journal open, 4(1), Article oead129. https://doi.org/10.1093/ehjopen/oead129
    • Gingele, A. J., Brandts, L., Vossen, K., Knackstedt, C., Boyne, J., & Rocca, H. P. B. L. (2024). Prognostic value of signs and symptoms in heart failure patients using remote telemonitoring. Journal of Telemedicine and Telecare, 30(1), 180–185. Article 1357633X211039404. https://doi.org/10.1177/1357633X211039404
    • Ament, S. M. C., van den Beuken-Everdingen, M., Maessen, J. M. C., Boyne, J., Schols, J. M. G. A., Stoffers, H. E. J. H., Bellersen, L., Brunner-La Rocca, H.-P., Engels, Y., & Janssen, D. J. A. (2024). Professionals guidance about palliative medicine in chronic heart failure: a mixed-method study. BMJ Supportive and Palliative Care, 14(e2), e1858-e1865. https://doi.org/10.1136/bmjspcare-2020-002580
  • 2023
    • Sewduth, R. N., Carai, P., Ivanisevic, T., Zhang, M., Jang, H., Lechat, B., Van Haver, D., Impens, F., Nussinov, R., Jones, E., & Sablina, A. (2023). Spatial Mechano-Signaling Regulation of GTPases through Non-Degradative Ubiquitination. Advanced Science, 10(36), Article 2303367. https://doi.org/10.1002/advs.202303367
    • Bellen, F., Carbone, E., Baatsen, P., Jones, E. A. V., Kabirian, F., & Heying, R. (2023). Improvement of Endothelial Cell-Polycaprolactone Interaction through Surface Modification via Aminolysis, Hydrolysis, and a Combined Approach. Journal of Tissue Engineering and Regenerative Medicine, 2023, Article 5590725. https://doi.org/10.1155/2023/5590725
    • Frey, S. M., Bakula, A., Tsirkin, A., Vasilchenko, V., Ruff, P., Oehri, C., Amrein, M. F., Huré, G., Rumora, K., Schäfer, I., Caobelli, F., Haaf, P., Mueller, C. E., Remppis, B. A., Rocca, H. P. B. L., & Zellweger, M. J. (2023). Artificial intelligence to improve ischemia prediction in Rubidium Positron Emission Tomography—a validation study. The EPMA Journal, 14(4), 631-643. https://doi.org/10.1007/s13167-023-00341-5
    • Knackstedt, C., Ramaekers, B., Schummers, G., Schreckenberg, M., Faessen, J., Marx, N., Becker, M., Sanders-van Wijk, S., van Empel, V., Norra, C., Kunert, H. J., Brunner-La Rocca, H.-P., & PsychEcho study group (2023). Influence of Individual Personality Traits of the Reader on Visual Assessment of Left Ventricular Ejection Fraction: Another Reason to Abandon Visual Assessment. Journal of the American Society of Echocardiography, 36(12), 1332-1335. https://doi.org/10.1016/j.echo.2023.08.015
    • Gingele, A. J., Amin, H., Vaassen, A., Schnur, I., Pearl, C., Brunner-La Rocca, H. P., & Boyne, J. (2023). Integrating avatar technology into a telemedicine application in heart failure patients A pilot study. Wiener Klinische Wochenschrift, 135(23-24), 680–684. https://doi.org/10.1007/s00508-022-02150-8
    • Hazebroek, M. R., & Verdonschot, J. A. J. (2023). One step closer to the new frontiers of healthcare for cardiomyopathy patients. Heart, 109(24), 1808-1810. https://doi.org/10.1136/heartjnl-2023-323095
    • Potjewijd, J., Tobal, R., Boomars, K. A., van Empel, V. V. P. M., de Vries, F., Damoiseaux, J. G. M. C., Schurgers, L. J., & van Paassen, P. (2023). Plasma Dephosphorylated-Uncarboxylated Matrix Gla-Protein in Systemic Sclerosis Patients: Biomarker Potential for Vascular Calcification and Inflammation. Diagnostics, 13(23), Article 3526. https://doi.org/10.3390/diagnostics13233526
    • Weerts, J., Amin, H., Barandiarán Aizpurua, A., Gevaert, A. B., Handoko, M. L., Dauw, J., Tun, H. N., Rommel, K.-P., Verbrugge, F. H., Kresoja, K.-P., Sanders-van Wijk, S., Brunner-La Rocca, H.-P., Bayés-Genís, A., Lumens, J., Knackstedt, C., & van Empel, V. P. M. (2023). Webtool to enhance the accuracy of diagnostic algorithms for HFpEF: a prospective cross-over study. Esc heart failure, 10(6), 3493 - 3503. https://doi.org/10.1002/ehf2.14525
    • Scholte, N. T., Aydin, D., Linssen, G. C., Koudstaal, S., Rademaker, P. C., Geerlings, P. R., van Gent, M. W., Aksoy, I., Oosterom, L., Boersma, E., Brunner-La Rocca, H.-P., & Brugts, J. J. (2023). Use of loop diuretics in patients with chronic heart failure: an observational overview. Open Heart, 10(2), Article e002497. https://doi.org/10.1136/openhrt-2023-002497
    • Meani, P., Pagnoni, M., Mondellini, G. M., Fiorenza, S., & Brunner-La Rocca, H. P. (2023). Impact of loop diuretic dosage in a population of patients with acute heart failure: a retrospective analysis. Frontiers in Cardiovascular Medicine, 10, Article 1267042. https://doi.org/10.3389/fcvm.2023.1267042
    • Ciccarelli, M., Pires, I. F., Bauersachs, J., Bertrand, L., Beauloye, C., Dawson, D., Hamdani, N., Hilfiker-Kleiner, D., van Laake, L. W., Lezoualc'h, F., Linke, W. A., Lunde, I. G., Rainer, P. P., Rispoli, A., Visco, V., Carrizzo, A., Ferro, M. D., Stolfo, D., van der Velden, J., ... Tocchetti, C. G. (2023). Acute heart failure: mechanisms and pre-clinical models-a Scientific Statement of the ESC Working Group on Myocardial Function. Cardiovascular Research, 119(14), 2390-2404. Article cvad088. https://doi.org/10.1093/cvr/cvad088
    • Bruninx, A., Geraeds, C., Brunner-La Rocca, H., Dekker, A., & Bermejo, I. (2023). Modelling clinicians' decisions to adjust loop diuretic dose based on patient-reported symptoms to inform decision-aids in daily care of chronic heart failure. European Heart Journal, 44.
    • Nelissen, E., Schepers, M., Ponsaerts, L., Foulquier, S., Bronckaers, A., Vanmierlo, T., Sandner, P., & Prickaerts, J. (2023). Soluble guanylyl cyclase: A novel target for the treatment of vascular cognitive impairment?Pharmacological Research, 197(1), Article 106970. https://doi.org/10.1016/j.phrs.2023.106970
    • Babu, V. S., Mallipatna, A., Dudeja, G., Shetty, R., Nair, A. P., Tun, S. B. B., Ho, C. E. H., Chaurasia, S. S., Bhattacharya, S. S., Verma, N. K., Lakshminarayanan, R., Guha, N., Heymans, S., Barathi, V. A., & Ghosh, A. (2023). Depleted hexokinase1 and lack of AMPKα activation favor OXPHOS-dependent energetics in retinoblastoma tumors. Translational Research, 261(1), 41-56. https://doi.org/10.1016/j.trsl.2023.07.001
    • Sikking, M. A., Stroeks, S. L. V. M., Marelli-Berg, F., Heymans, S. R. B., Ludewig, B., & Verdonschot, J. A. J. (2023). Immunomodulation of Myocardial Fibrosis. JACC: Basic to Translational Science, 8(11), 1477-1488. https://doi.org/10.1016/j.jacbts.2023.03.015
    • Schoonvelde, S. A. C., Ruijmbeek, C. W. B., Hirsch, A., van Slegtenhorst, M. A., Wessels, M. W., von der Thusen, J. H., Baas, A. F., Stroeks, S. L. V. M., Verdonschot, J. A. J., van der Zwaag, P. A., Verhagen, J. M. A., & Michels, M. (2023). Phenotypic Variability of Filamin C-related Cardiomyopathy: Insights from a Novel Dutch Founder Variant. Heart Rhythm, 20(11), 1512-1521. https://doi.org/10.1016/j.hrthm.2023.08.003
    • Seferovic, P. M., Polovina, M., Rosano, G., Bozkurt, B., Metra, M., Heymans, S., Mullens, W., Bauersachs, J., Sliwa, K., de Boer, R. A., Farmakis, D., Thum, T., Olivotto, I., Rapezzi, C., Linhart, A., Corrado, D., Tschöpe, C., Milinkovic, I., Bayes Genis, A., ... Coats, A. J. (2023). State-of-the-art document on optimal contemporary management of cardiomyopathies. European journal of heart failure, 25(11), 1899-1922. Article ejhf2979. https://doi.org/10.1002/ejhf.2979
    • Berends, E., van Oostenbrugge, R. J., Foulquier, S., & Schalkwijk, C. G. (2023). Methylglyoxal, a highly reactive dicarbonyl compound, as a threat for blood brain barrier integrity. Fluids and barriers of the CNS, 20(1), Article 75. https://doi.org/10.1186/s12987-023-00477-6
    • Michelly Gonçalves Brandão, S., Brunner-La Rocca, H. P., Pedroso De Lima, A. C., & Alcides Bocchi, E. (2023). A review of cost-effectiveness analysis: From theory to clinical practice. Medicine, 102(42), Article e35614. https://doi.org/10.1097/MD.0000000000035614
    • McDonagh, T. A., Metra, M., Adamo, M., Gardner, R. S., Baumbach, A., Böhm, M., Burri, H., Butler, J., Celutkiene, J., Chioncel, O., Cleland, J. G. F., Crespo-Leiro, M. G., Farmakis, D., Gilard, M., Heymans, S., Hoes, A. W., Jaarsma, T., Jankowska, E. A., Lainscak, M., ... ESC Scientific Document Group (2023). 2023 Focused Update of the 2021 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure Developed by the task force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) With the special contribution of the Heart Failure Association (HFA) of the ESC. European Heart Journal, 44(37), 3627-3639. https://doi.org/10.1093/eurheartj/ehad195
    • Giudici, A., van der Laan, K. W. F., van der Bruggen, M. M., Parikh, S., Berends, E., Foulquier, S., Delhaas, T., Reesink, K. D., & Spronck, B. (2023). Constituent-based quasi-linear viscoelasticity: a revised quasi-linear modelling framework to capture nonlinear viscoelasticity in arteries. Biomechanics and modeling in mechanobiology, 22(5), 1607–1623. https://doi.org/10.1007/s10237-023-01711-8
    • Heymans, S., Lakdawala, N. K., Tschöpe, C., & Klingel, K. (2023). Dilated cardiomyopathy: causes, mechanisms, and current and future treatment approaches. Lancet, 402(10406), 998-1011. https://doi.org/10.1016/S0140-6736(23)01241-2
    • Kerstens, T. P., Weerts, J., van Dijk, A. P. J., Weijers, G., Knackstedt, C., Eijsvogels, T. M. H., Oxborough, D., van Empel, V. P. M., & Thijssen, D. H. J. (2023). Association of left ventricular strain-volume loop characteristics with adverse events in patients with heart failure with preserved ejection fraction. European Heart Journal Cardiovascular Imaging, 24(9), 1168-1176. https://doi.org/10.1093/ehjci/jead117
    • Raafs, A. G., Adriaans, B. P., Henkens, M. T. H. M., Verdonschot, J. A. J., Abdul Hamid, M. A., Díez, J., Knackstedt, C., van Empel, V. P. M., Brunner-La Rocca, H. P., González, A., Wildberger, J. E., Heymans, S. R. B., & Hazebroek, M. R. (2023). Biomarkers of Collagen Metabolism Are Associated with Left Ventricular Function and Prognosis in Dilated Cardiomyopathy: A Multi-Modal Study. Journal of Clinical Medicine, 12(17), Article 5695. https://doi.org/10.3390/jcm12175695
    • Meijs, C., Brugts, J. J., Lund, L. H., Linssen, G. C. M., Brunner-La Rocca, H.-P., Dahlstrom, U., Vaartjes, I., Koudstaal, S., Asselbergs, F. W., Savarese, G., & Uijl, A. (2023). Identifying distinct clinical clusters in heart failure with mildly reduced ejection fraction. International Journal of Cardiology, 386(1), 83-90. https://doi.org/10.1016/j.ijcard.2023.05.024
    • Canto, E. D., van Deursen, L., Hoek, A. G., Elders, P. J. M., den Ruijter, H. M., van der Velden, J., van Empel, V., Serné, E. H., Eringa, E. C., & Beulens, J. W. J. (2023). Microvascular endothelial dysfunction in skin is associated with higher risk of heart failure with preserved ejection fraction in women with type 2 diabetes: the Hoorn Diabetes Care System Cohort. Cardiovascular Diabetology, 22(1), Article 234. https://doi.org/10.1186/s12933-023-01935-z
    • Bednarska, K., Fecka, I., Scheijen, J. L. J. M., Ahles, S., Vangrieken, P., & Schalkwijk, C. G. (2023). A Citrus and Pomegranate Complex Reduces Methylglyoxal in Healthy Elderly Subjects: Secondary Analysis of a Double-Blind Randomized Cross-Over Clinical Trial. International Journal of Molecular Sciences, 24(17), Article 13168. https://doi.org/10.3390/ijms241713168
    • Malgie, J., Clephas, P. R. D., Brunner-La Rocca, H.-P., de Boer, R. A., & Brugts, J. J. (2023). Guideline-directed medical therapy for HFrEF: sequencing strategies and barriers for life-saving drug therapy. Heart Failure Reviews, 28(5), 1221-1234. https://doi.org/10.1007/s10741-023-10325-2
    • Vos, J. L., Raafs, A. G., Henkens, M. T. H. M., Pedrizzetti, G., van Deursen, C. J., Rodwell, L., Heymans, S. R. B., & Nijveldt, R. (2023). CMR-derived left ventricular intraventricular pressure gradients identify different patterns associated with prognosis in dilated cardiomyopathy. European Heart Journal Cardiovascular Imaging, 24(9), 1231-1240. https://doi.org/10.1093/ehjci/jead083
    • Manukjan, N., Majcher, D., Leenders, P., Caiment, F., van Herwijnen, M., Smeets, H. J. J., Suidgeest, E., van der Weerd, L., Vanmierlo, T., Jansen, J. F. A., Backes, W. H. H., van Oostenbrugge, R. J. J., Staals, J., Fulton, D., Ahmed, Z., Blankesteijn, W. M., & Foulquier, S. (2023). Hypoxic oligodendrocyte precursor cell-derived VEGFA is associated with blood-brain barrier impairment. Acta neuropathologica communications, 11(1), Article 128. https://doi.org/10.1186/s40478-023-01627-5
    • Habibi, Z., Abma-Kramer, J., & Brunner-La Rocca, H.-P. (2023). A case report of high-output heart failure due to arteriovenous shunt without bowel: how to address?European Heart Journal - Case Reports, 7(8), Article ytad360. https://doi.org/10.1093/ehjcr/ytad360
    • Sikking, M. A., Stroeks, S. L. V. M., Waring, O. J., Henkens, M. T. H. M., Riksen, N. P., Hoischen, A., Heymans, S. R. B., & Verdonschot, J. A. J. (2023). Clonal Hematopoiesis of Indeterminate Potential From a Heart Failure Specialist’s Point of View. Journal of the American Heart Association, 12(15), Article e030603. https://doi.org/10.1161/JAHA.123.030603
    • Jones, E. A. V. (2023). Mechanism of COVID-19-Induced Cardiac Damage from Patient, In Vitro and Animal Studies. Current Heart Failure Reports, 20(5), 451-460. https://doi.org/10.1007/s11897-023-00618-w
    • O'Neill, M. J., Chen, S. N., Rumping, L., Johnson, R., van Slegtenhorst, M., Glazer, A. M., Yang, T., Solus, J. F., Laudeman, J., Mitchell, D. W., Vanags, L. R., Kroncke, B. M., Anderson, K., Gao, S., Verdonschot, J. A. J., Brunner, H., Hellebrekers, D., Taylor, M. R. G., Roden, D. M., ... Shoemaker, M. B. (2023). Multicenter clinical and functional evidence reclassifies a recurrent noncanonical filamin C splice-altering variant. Heart Rhythm, 20(8), 1158-1166. https://doi.org/10.1016/j.hrthm.2023.05.006
    • Kobayashi, M., Huttin, O., Ferreira, J. P., Duarte, K., Gonzalez, A., Heymans, S., Verdonschot, J. A. J., Brunner-La Rocca, H.-P., Pellicori, P. L., Clark, A., Petutschnigg, J., Edelmann, F. G., Cleland, J., Rossignol, P., Zannad, F., Girerd, N., & HOMAGE Trial Committees and Investigators (2023). A machine learning-derived echocardiographic algorithm identifies people at risk of heart failure with distinct cardiac structure, function, and response to spironolactone: findings from the HOMAGE trial. European journal of heart failure, 25(8), 1284-1289. https://doi.org/10.1002/ejhf.2859
    • Heymans, S., & Cooper, L. T. (2023). Author Correction: Myocarditis after COVID-19 mRNA vaccination: clinical observations and potential mechanisms. Nature Reviews Cardiology, 20(8), 575-575. https://doi.org/10.1038/s41569-023-00904-z
    • Vinke, J. S. J., Gorter, A. R., Eisenga, M. F., Dam, W. A., van der Meer, P., van den Born, J., Bakker, S. J. L., Hoes, M. F., & de Borst, M. H. (2023). Iron deficiency is related to lower muscle mass in community-dwelling individuals and impairs myoblast proliferation. Journal of cachexia, sarcopenia and muscle, 14(4), 1865-1879. https://doi.org/10.1002/jcsm.13277