Heymans, S., Lakdawala, N. K., Tschöpe, C., & Klingel, K. (2023). Dilated cardiomyopathy: causes, mechanisms, and current and future treatment approaches. Lancet, 402(10406), 998-1011. https://doi.org/10.1016/S0140-6736(23)01241-2

Kerstens, T. P., Weerts, J., van Dijk, A. P. J., Weijers, G., Knackstedt, C., Eijsvogels, T. M. H., Oxborough, D., van Empel, V. P. M., & Thijssen, D. H. J. (2023). Association of left ventricular strain-volume loop characteristics with adverse events in patients with heart failure with preserved ejection fraction. European Heart Journal Cardiovascular Imaging, 24(9), 1168-1176. https://doi.org/10.1093/ehjci/jead117

Raafs, A. G., Adriaans, B. P., Henkens, M. T. H. M., Verdonschot, J. A. J., Abdul Hamid, M. A., Díez, J., Knackstedt, C., van Empel, V. P. M., Brunner-La Rocca, H. P., González, A., Wildberger, J. E., Heymans, S. R. B., & Hazebroek, M. R. (2023). Biomarkers of Collagen Metabolism Are Associated with Left Ventricular Function and Prognosis in Dilated Cardiomyopathy: A Multi-Modal Study. Journal of Clinical Medicine, 12(17), Article 5695. https://doi.org/10.3390/jcm12175695

Meijs, C., Brugts, J. J., Lund, L. H., Linssen, G. C. M., Brunner-La Rocca, H.-P., Dahlstrom, U., Vaartjes, I., Koudstaal, S., Asselbergs, F. W., Savarese, G., & Uijl, A. (2023). Identifying distinct clinical clusters in heart failure with mildly reduced ejection fraction. International Journal of Cardiology, 386(1), 83-90. https://doi.org/10.1016/j.ijcard.2023.05.024

Canto, E. D., van Deursen, L., Hoek, A. G., Elders, P. J. M., den Ruijter, H. M., van der Velden, J., van Empel, V., Serné, E. H., Eringa, E. C., & Beulens, J. W. J. (2023). Microvascular endothelial dysfunction in skin is associated with higher risk of heart failure with preserved ejection fraction in women with type 2 diabetes: the Hoorn Diabetes Care System Cohort. Cardiovascular Diabetology, 22(1), Article 234. https://doi.org/10.1186/s12933-023-01935-z

Bednarska, K., Fecka, I., Scheijen, J. L. J. M., Ahles, S., Vangrieken, P., & Schalkwijk, C. G. (2023). A Citrus and Pomegranate Complex Reduces Methylglyoxal in Healthy Elderly Subjects: Secondary Analysis of a Double-Blind Randomized Cross-Over Clinical Trial. International Journal of Molecular Sciences, 24(17), Article 13168. https://doi.org/10.3390/ijms241713168

Malgie, J., Clephas, P. R. D., Brunner-La Rocca, H.-P., de Boer, R. A., & Brugts, J. J. (2023). Guideline-directed medical therapy for HFrEF: sequencing strategies and barriers for life-saving drug therapy. Heart Failure Reviews, 28(5), 1221-1234. https://doi.org/10.1007/s10741-023-10325-2

Vos, J. L., Raafs, A. G., Henkens, M. T. H. M., Pedrizzetti, G., van Deursen, C. J., Rodwell, L., Heymans, S. R. B., & Nijveldt, R. (2023). CMR-derived left ventricular intraventricular pressure gradients identify different patterns associated with prognosis in dilated cardiomyopathy. European Heart Journal Cardiovascular Imaging, 24(9), 1231-1240. https://doi.org/10.1093/ehjci/jead083

Manukjan, N., Majcher, D., Leenders, P., Caiment, F., van Herwijnen, M., Smeets, H. J. J., Suidgeest, E., van der Weerd, L., Vanmierlo, T., Jansen, J. F. A., Backes, W. H. H., van Oostenbrugge, R. J. J., Staals, J., Fulton, D., Ahmed, Z., Blankesteijn, W. M., & Foulquier, S. (2023). Hypoxic oligodendrocyte precursor cell-derived VEGFA is associated with blood-brain barrier impairment. Acta neuropathologica communications, 11(1), Article 128. https://doi.org/10.1186/s40478-023-01627-5

Habibi, Z., Abma-Kramer, J., & Brunner-La Rocca, H.-P. (2023). A case report of high-output heart failure due to arteriovenous shunt without bowel: how to address?European Heart Journal - Case Reports, 7(8), Article ytad360. https://doi.org/10.1093/ehjcr/ytad360

Sikking, M. A., Stroeks, S. L. V. M., Waring, O. J., Henkens, M. T. H. M., Riksen, N. P., Hoischen, A., Heymans, S. R. B., & Verdonschot, J. A. J. (2023). Clonal Hematopoiesis of Indeterminate Potential From a Heart Failure Specialist’s Point of View. Journal of the American Heart Association, 12(15), Article e030603. https://doi.org/10.1161/JAHA.123.030603

Jones, E. A. V. (2023). Mechanism of COVID-19-Induced Cardiac Damage from Patient, In Vitro and Animal Studies. Current Heart Failure Reports, 20(5), 451-460. https://doi.org/10.1007/s11897-023-00618-w

O'Neill, M. J., Chen, S. N., Rumping, L., Johnson, R., van Slegtenhorst, M., Glazer, A. M., Yang, T., Solus, J. F., Laudeman, J., Mitchell, D. W., Vanags, L. R., Kroncke, B. M., Anderson, K., Gao, S., Verdonschot, J. A. J., Brunner, H., Hellebrekers, D., Taylor, M. R. G., Roden, D. M., ... Shoemaker, M. B. (2023). Multicenter clinical and functional evidence reclassifies a recurrent noncanonical filamin C splice-altering variant. Heart Rhythm, 20(8), 1158-1166. https://doi.org/10.1016/j.hrthm.2023.05.006

Kobayashi, M., Huttin, O., Ferreira, J. P., Duarte, K., Gonzalez, A., Heymans, S., Verdonschot, J. A. J., Brunner-La Rocca, H.-P., Pellicori, P. L., Clark, A., Petutschnigg, J., Edelmann, F. G., Cleland, J., Rossignol, P., Zannad, F., Girerd, N., & HOMAGE Trial Committees and Investigators (2023). A machine learning-derived echocardiographic algorithm identifies people at risk of heart failure with distinct cardiac structure, function, and response to spironolactone: findings from the HOMAGE trial. European journal of heart failure, 25(8), 1284-1289. https://doi.org/10.1002/ejhf.2859

Heymans, S., & Cooper, L. T. (2023). Author Correction: Myocarditis after COVID-19 mRNA vaccination: clinical observations and potential mechanisms. Nature Reviews Cardiology, 20(8), 575-575. https://doi.org/10.1038/s41569-023-00904-z

Vinke, J. S. J., Gorter, A. R., Eisenga, M. F., Dam, W. A., van der Meer, P., van den Born, J., Bakker, S. J. L., Hoes, M. F., & de Borst, M. H. (2023). Iron deficiency is related to lower muscle mass in community-dwelling individuals and impairs myoblast proliferation. Journal of cachexia, sarcopenia and muscle, 14(4), 1865-1879. https://doi.org/10.1002/jcsm.13277

van Mourik, M. J. W., Linz, D., Verwijs, H. J. A., Bekkers, S. C. A. M., Weerts, J., Schotten, U., Rocca, H. B.-L., Lumens, J., Crijns, H. J. G. M., Weijs, B., & Knackstedt, C. (2023). Evaluating subclinical left ventricular and left atrial dysfunction in idiopathic atrial fibrillation: A speckle-tracking based strain-analysis. International Journal of Cardiology, 383(1), 159-165. https://doi.org/10.1016/j.ijcard.2023.04.024

Kerkhofs, D., Helgers, R., Hermes, D., Steinbusch, H. P. J., Van Essen, H., Leenders, P., Prickaerts, J., Staals, J., Biessen, E. A., Van Oostenbrugge, R. J., & Foulquier, S. (2023). Amlodipine limits microglia activation and cognitive dysfunction in aged hypertensive mice. Journal of Hypertension, 41(7), 1159-1167. https://doi.org/10.1097/HJH.0000000000003445

Rabussier, G., Bunter, I., Bouwhuis, J., Soragni, C., van Zijp, T., Ng, C. P., Domansky, K., Windt, L. J. D., Vulto, P., Murdoch, C. E., Bircsak, K. M., & Lanz, H. L. (2023). Healthy and diseased placental barrier on-a-chip models suitable for standardized studies. Acta Biomaterialia, 164(1), 363-376. https://doi.org/10.1016/j.actbio.2023.04.033

Colin, M., Delaitre, C., Foulquier, S., & Dupuis, F. (2023). The AT(1)/AT(2) Receptor Equilibrium Is a Cornerstone of the Regulation of the Renin Angiotensin System beyond the Cardiovascular System. Molecules, 28(14), Article 5481. https://doi.org/10.3390/molecules28145481

Stroeks, S. L. V. M., Hellebrekers, D., Claes, G. R. F., Krapels, I. P. C., Henkens, M. H. T. M., Sikking, M., Vanhoutte, E. K., van den Enden, A. T. J. M. H., Brunner, H. G., van den Wijngaard, A., & Verdonschot, J. A. J. (2023). Diagnostic and prognostic relevance of using large gene panels in the genetic testing of patients with dilated cardiomyopathy. European Journal of Human Genetics, 31(7), 776-783. https://doi.org/10.1038/s41431-023-01384-y

Aga, Y. S., Radhoe, S. P., Aydin, D., Linssen, G. C. M., Rademaker, P. C., Geerlings, P. R., van Gent, M. W. F., Aksoy, I., Oosterom, L., Brunner-La Rocca, H. P. B. L., van Dalen, B. M., & Brugts, J. J. (2023). Heart failure treatment in patients with and without obesity with an ejection fraction below 50%. European Journal of Clinical Investigation, 53(7), Article e13976. https://doi.org/10.1111/eci.13976

Brugts, J. J., Radhoe, S. P., Clephas, P. R. D., Aydin, D., van Gent, M. W. F., Szymanski, M. K., Rienstra, M., van den Heuvel, M. H., da Fonseca, C. A., Linssen, G. C. M., Borleffs, C. J. W., Boersma, E., Asselbergs, F. W., Mosterd, A., Brunner-La Rocca, H. P., de Boer, R. A., Emans, M. E., Beeres, S. L. M. A., Heerebeek, L., ... MONITOR-HF investigators (2023). Remote haemodynamic monitoring of pulmonary artery pressures in patients with chronic heart failure (MONITOR-HF): a randomised clinical trial. Lancet, 401(10394), 2113-2123. https://doi.org/10.1016/S0140-6736(23)00923-6

Juni, R. P., Kocken, J. M. M., Abreu, R. C., Ottaviani, L., Davalan, T., Duygu, B., Poels, E. M., Vasilevich, A., Hegenbarth, J. C., Appari, M., Bitsch, N., Olieslagers, S., Schrijvers, D. M., Stoll, M., Heineke, J., de Boer, J., de Windt, L. J., & da Costa, P. A. (2023). MicroRNA-216a is essential for cardiac angiogenesis. Molecular Therapy, 31(6), 1807-1828. https://doi.org/10.1016/j.ymthe.2023.04.007

ter Bekke, R. M. A., de Schouwer, K., Conti, S., Claes, G. R. F., Vanoevelen, J., Gommers, S., Helderman-van den Enden, A. T. J. M., & Brunner-LaRocca, H.-P. (2023). Juvenile-onset multifocal atrial arrhythmias, atrial standstill and compound heterozygosity of genetic variants in TAF1A: sentinel event for evolving dilated cardiomyopathy-a case report. European Heart Journal - Case Reports, 7(6), Article ytad255. https://doi.org/10.1093/ehjcr/ytad255

Callewaert, B., Gsell, W., Himmelreich, U., & Jones, E. A. V. (2023). Q-VAT: Quantitative Vascular Analysis Tool. Frontiers in Cardiovascular Medicine, 10, Article 1147462. https://doi.org/10.3389/fcvm.2023.1147462

Sikking, M. A., Stroeks, S. L. V. M., Henkens, M. T. H. M., Venner, M. F. G. H. M., Li, X., Heymans, S. R. B., Hazebroek, M. R., & Verdonschot, J. A. J. (2023). Cardiac Inflammation in Adult-Onset Genetic Dilated Cardiomyopathy. Journal of Clinical Medicine, 12(12), Article 3937. https://doi.org/10.3390/jcm12123937

Steiner, B., Neumann, A., Pelz, Y., Ski, C. F., Hill, L., Thompson, D. R., Fitzsimons, D., Dixon, L. J., Brandts, J., Verket, M., Schuett, K., Eurlings, C. G. M. J., Boyne, J. J. J., Gingele, A. J., De Maesschalck, L., Murphy, M., da Luz, E. F., Barrett, M., Windle, K., ... PASSION-HF consortium (2023). Challenges in heart failure care in four European countries: a comparative study. European Journal of Public Health, 33(3), 448-454. https://doi.org/10.1093/eurpub/ckad059

Linders, A. N., Dias, I. B., Ovchinnikova, E. S., Vermeer, M. C. S. C., Hoes, M. F., Mavrogenis, G. M., Deiman, F. E., Gomez, K. F. A., Bliley, J. M., Nehme, J., Vink, A., Gietema, J., de Boer, R. A., Westenbrink, D., Sillje, H. H. W., Hilfiker-Kleiner, D., van Laake, L. W., Feinberg, A. W., Demaria, M., ... van der Meer, P. (2023). Evaluation of Senescence and Its Prevention in Doxorubicin-Induced Cardiotoxicity Using Dynamic Engineered Heart Tissues. JACC: CardioOncology, 5(3), 298-315. https://doi.org/10.1016/j.jaccao.2023.03.012

Stroeks, S. L. V. M., & Verdonschot, J. A. J. (2023). The next step toward personalized recommendations for genetic cardiomyopathies. European Journal of Human Genetics, 31(11), 1201 - 1203. https://doi.org/10.1038/s41431-023-01394-w

Gorter, T. M., van Veldhuisen, D. J., Mulder, B. A., Arita, V. A. A. A., van Empel, V. P. M., Manintveld, O. C., Tieleman, R. G., Maass, A. H., Vernooy, K., van Gelder, I. C., & Rienstra, M. (2023). Prevalence and Incidence of Atrial Fibrillation in Heart Failure with Mildly Reduced or Preserved Ejection Fraction: (Additive) Value of Implantable Loop Recorders. Journal of Clinical Medicine, 12(11), Article 3682. https://doi.org/10.3390/jcm12113682

Vermeer, M. C. S. C., Arevalo Gomez, K. F., Hoes, M. F., Tromp, J., Verdonschot, J. A. J., Henkens, M. T. H. M., Silljé, H. H. W., Bolling, M. C., & van der Meer, P. (2023). Clinical Outcome in KLHL24 Cardiomyopathy. Circulation: Genomic and Precision Medicine, 16(4), 401-403. https://doi.org/10.1161/CIRCGEN.122.003998

Kerstens, T. P., Weerts, J., van Dijk, A. P. J., Weijers, G., Knackstedt, C., Eijsvogels, T. M. H., Oxborough, D., van Empel, V. P. M., & Thijssen, D. H. J. (2023). Left ventricular strain-volume loops and diastolic dysfunction in suspected heart failure with preserved ejection fraction. International Journal of Cardiology, 378(1), 144-150. https://doi.org/10.1016/j.ijcard.2023.01.084

Girerd, N., Levy, D., Duarte, K., Ferreira, J. P., Ballantyne, C., Collier, T., Pizard, A., Björkman, J., Butler, J., Clark, A., Cleland, J. G., Delles, C., Diez, J., González, A., Hazebroek, M., Ho, J., Huby, A. C., Hwang, S. J., Latini, R., ... Zannad, F. (2023). Protein Biomarkers of New-Onset Heart Failure: Insights From the Heart Omics and Ageing Cohort, the Atherosclerosis Risk in Communities Study, and the Framingham Heart Study. Circulation-Heart Failure, 16(5), 426-441. Article e009694. https://doi.org/10.1161/CIRCHEARTFAILURE.122.009694

Knackstedt, C., Schummers, G., Schroder, J., Marx, N., Lumens, J., Sanders-van Wijk, S., Ramaekers, B., Becker, M., van Empel, V., Brunner-La Rocca, H. P., & PsychEcho study group (2023). A graphical analysis of aspects contributing to the spreading of measurements of left ventricular function. International Journal of Cardiovascular Imaging, 39(5), 915-927. https://doi.org/10.1007/s10554-023-02796-z

Starmans, N. L., Wolters, F. J., Leeuwis, A. E., Bron, E. E., La Rocca, H. P. B., Staals, J., Biessels, G. J., & Kappelle, L. J. (2023). Twenty-four hour blood pressure variability and the prevalence and the progression of cerebral white matter hyperintensities. Journal of Cerebral Blood Flow and Metabolism, 43(5), 801-811. https://doi.org/10.1177/0271678X221149937

Verdonschot, J. A. J., Wang, P., Derks, K. W. J., Adriaens, M. E., Stroeks, S. L. V. M., Henkens, M. T. H. M., Raafs, A. G., Sikking, M., de Koning, B., van den Wijngaard, A., Krapels, I. P. C., Nabben, M., Brunner, H. G., & Heymans, S. R. B. (2023). Clustering of Cardiac Transcriptome Profiles Reveals Unique Subgroups of Dilated Cardiomyopathy Patients. JACC: Basic to Translational Science, 8(4), 406-418. https://doi.org/10.1016/j.jacbts.2022.10.010

Stroeks, S. L. V. M., Lunde, I. G. G., Hellebrekers, D. M. E. I., Claes, G. R. F., Wakimoto, H., Gorham, J., Krapels, I. P. C., Vanhoutte, E. K. K., van den Wijngaard, A., Henkens, M. T. H. M., Raafs, A. G. G., Sikking, M. A. A., Broers, J. L. V., Nabben, M., Jones, E. A. V., Heymans, S. R. B., Brunner, H. G. G., & Verdonschot, J. A. J. (2023). Prevalence and Clinical Consequences of Multiple Pathogenic Variants in Dilated Cardiomyopathy. Circulation: Genomic and Precision Medicine, 16(2), Article e003788. https://doi.org/10.1161/CIRCGEN.122.003788

Clephas, P. R. D., Radhoe, S. P., Linssen, G. C. M., Langerveld, J., Plomp, J., Smits, J. P. P., Nagelsmit, M. J., Rocca, H. P. B. L., & Brugts, J. J. (2023). Serum potassium level and mineralocorticoid receptor antagonist dose in a large cohort of chronic heart failure patients. Esc heart failure, 10(2), 1481-1487. https://doi.org/10.1002/ehf2.14285

Soragni, C., Vergroesen, T., Hettema, N., Rabussier, G., Lanz, H. L., Trietsch, S. J., de Windt, L. J., & Ng, C. P. (2023). Quantify permeability using on-a-chip models in high-throughput applications. STAR protocols, 4(1), Article 102051. https://doi.org/10.1016/j.xpro.2023.102051

Ferreira, J. P., Cleland, J. G. F., Girerd, N., Pellicori, P., Hazebroek, M. R., Verdonschot, J., Collier, T. J., Petutschnigg, J., Clark, A. L., Staessen, J. A., Heymans, S., Rossignol, P., & Zannad, F. (2023). Effect of Spironolactone on QRS Duration in Patients at Risk for Heart Failure (from the HOMAGE Trial). American Journal of Cardiology, 191(1), 39-42. https://doi.org/10.1016/j.amjcard.2022.12.016

Robinson, E. L., Ameri, P., Delrue, L., Vanderheyden, M., Bartunek, J., Altieri, P., Heymans, S., & Heggermont, W. A. (2023). Differential expression of epigenetic modifiers in early and late cardiotoxic heart failure reveals DNA methylation as a key regulator of cardiotoxicity. Frontiers in Cardiovascular Medicine, 10(1), Article 884174. https://doi.org/10.3389/fcvm.2023.884174

Radhoe, S. P., Clephas, P. R. D., Linssen, G. C. M., Oortman, R. M., Smeele, F. J., Van Drimmelen, A. A., Schaafsma, H. J., Westendorp, P. H., Rocca, H. P. B. L., & Brugts, J. J. (2023). Phenotypic patient profiling for improved implementation of guideline-directed medical therapy: An exploratory analysis in a large real-world chronic heart failure cohort. Frontiers in Pharmacology, 14(1), Article 1081579. https://doi.org/10.3389/fphar.2023.1081579

de Boer, M., Hekkert, M. T., Chang, J., van Thiel, B. S., Martens, L., Bos, M. M., de Kleijnen, M. G. J., Ridwan, Y., Octavia, Y., van Deel, E. D., Blonden, L. A., Brandt, R. M. C., Barnhoorn, S., Bautista-Nino, P. K., Krabbendam-Peters, I., Wolswinkel, R., Arshi, B., Ghanbari, M., Kupatt, C., ... Duncker, D. J. (2023). DNA repair in cardiomyocytes is critical for maintaining cardiac function in mice. Aging Cell, 22(3), Article e13768. https://doi.org/10.1111/acel.13768

Sanchez-Aguilera, P., Lopez-Crisosto, C., Norambuena-Soto, I., Penannen, C., Zhu, J. M., Bomer, N., Hoes, M. F., van der Meer, P., Chiong, M., Westenbrink, B. D., & Lavandero, S. (2023). IGF-1 boosts mitochondrial function by a Ca2+ uptake-dependent mechanism in cultured human and rat cardiomyocytes. Frontiers in physiology, 14(1), Article 1106662. https://doi.org/10.3389/fphys.2023.1106662

Stroeks, S. L. V. M., van Beek, D., Adriaens, M. E., & Verdonschot, J. A. J. (2023). Titin Allelic Expression and Protein Processing Pathways in Early-Stage Dilated Cardiomyopathy Patients With Truncating Titin Variants. Circulation: Genomic and Precision Medicine, 16(1), 90-91. Article e003901. https://doi.org/10.1161/circgen.122.003901

Ferreira, J. P., Cleland, J. G. F., Girerd, N., Pellicori, P., Hazebroek, M. R., Verdonschot, J., Collier, T. J., Petutschnigg, J., Clark, A. L., Staessen, J. A., Heymans, S., Zannad, F., & Rossignol, P. (2023). Early and late renal function changes with spironolactone in patients at risk of developing heart failure: findings from the HOMAGE trial. Clinical research in cardiology, 112(2), 330-332. https://doi.org/10.1007/s00392-022-02116-w

Nuzzi, V., Raafs, A., Manca, P., Henkens, M. T. H. M., Gregorio, C., Boscutti, A., Verdonschot, J., Hazebroek, M., Knackstedt, C., Merlo, M., Stolfo, D., Sinagra, G., & Heymans, S. R. B. (2023). Left Atrial Reverse Remodeling in Dilated Cardiomyopathy. Journal of the American Society of Echocardiography, 36(2), 154-162. https://doi.org/10.1016/j.echo.2022.10.017

Luo, H., Weerts, J., Bekkers, A., Achten, A., Lievens, S., Smeets, K., van Empel, V., Delhaas, T., & Prinzen, F. W. (2023). Association between phonocardiography and echocardiography in heart failure patients with preserved ejection fraction. European Heart Journal - Digital Health, 4(1), 4-11. https://doi.org/10.1093/ehjdh/ztac073

van Beek, D., Verdonschot, J., Derks, K., Brunner, H., de Kok, T., Arts, I., Heymans, S., Kutmon, M., & Adriaens, M. (2023). Allele-specific expression analysis for complex genetic phenotypes applied to a unique dilated cardiomyopathy cohort. Scientific Reports, 13(1), Article 564. https://doi.org/10.1038/s41598-023-27591-7