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van Sloten, T. T., Pijpers, E., Stehouwer, C. D. A., & Brouwers, M. C. (2012). Metformin-associated lactic acidosis in a patient with normal kidney function.Diabetes Research and Clinical Practice, 96(3), E57-E58. https://doi.org/10.1016/j.diabres.2011.07.021

Brouwers, M. C. G. J., van Greevenbroek, M. M. J., Stehouwer, C. D. A., de Graaf, J., & Stalenhoef, A. F. H. (2012). The genetics of familial combined hyperlipidaemia. Nature Reviews Endocrinology, 8(6), 352-362. https://doi.org/10.1038/nrendo.2012.15

Simsek, S., Schalkwijk, C. G., & Wolffenbuttel, B. H. R. (2012). Effects of rosuvastatin and atorvastatin on glycaemic control in Type 2 diabetes-the CORALL study. Diabetic Medicine, 29(5), 628-631. https://doi.org/10.1111/j.1464-5491.2011.03553.x

Tailleux, A., Wouters, K., & Staels, B. (2012). Roles of PPARs in NAFLD: potential therapeutic targets. Biochimica et Biophysica Acta. Mucoproteins and Mucopolysaccharides, 1821(5), 809-18. https://doi.org/10.1016/j.bbalip.2011.10.016

Hertle, E., van Greevenbroek, M. M. J., & Stehouwer, C. D. A. (2012). Complement C3: an emerging risk factor in cardiometabolic disease. Diabetologia, 55(4), 881-884. https://doi.org/10.1007/s00125-012-2462-z

Schalkwijk, C. G., & Miyata, T. (2012). Early- and advanced non-enzymatic glycation in diabetic vascular complications: the search for therapeutics. Amino Acids, 42(4), 1193-1204. https://doi.org/10.1007/s00726-010-0779-9

Vaarhorst, A. A. M., Lu, Y., Heijmans, B. T., Dolle, M. E. T., Boehringer, S., Putter, H., Imholz, S., Merry, A. H. H., van Greevenbroek, M. M., Jukema, J. W., Gorgels, A. P. M., van den Brandt, P. A., Mueller, M., Schouten, L. J., Feskens, E. J. M., Boer, J. M. A., & Slagboom, P. E. (2012). Literature-Based Genetic Risk Scores for Coronary Heart Disease The Cardiovascular Registry Maastricht (CAREMA) Prospective Cohort Study. Circulation : Cardiovascular Genetics, 5(2), 202-209. https://doi.org/10.1161/CIRCGENETICS.111.960708

Bieghs, V., Verheyen, F., van Gorp, P. J., Hendrikx, T., Wouters, K., Lutjohann, D., Gijbels, M. J., Febbraio, M., Binder, C. J., Hofker, M. H., & Sverdlov, R. (2012). Internalization of modified lipids by cd36 and sr-a leads to hepatic inflammation and lysosomal cholesterol storage in kupffer cells. PLOS ONE, 7(3), Article e34378. https://doi.org/10.1371/journal.pone.0034378

Wouters, K., Cudejko, C., Gijbels, M. J. J., Fuentes, L., Bantubungi, K., Vanhoutte, J., Dievart, R., Paquet, C., Bouchaert, E., Hannou, S. A., Gizard, F., Tailleux, A., de Winther, M. P. J., Staels, B., & Paumelle, R. (2012). Bone Marrow p16(INK4a)-Deficiency Does Not Modulate Obesity, Glucose Homeostasis or Atherosclerosis Development. PLOS ONE, 7(3), e32440. https://doi.org/10.1371/journal.pone.0032440

Gaens, K. H. J., Niessen, P. M. G., Rensen, S. S., Buurman, W. A., Greve, J. W. M., Driessen, A., Wolfs, M. G. M., Hofker, M. H., Bloemen, J. G., Dejong, C. H., Stehouwer, C. D. A., & Schalkwijk, C. G. (2012). Endogenous formation of Nε(carboxymethyl)lysine is increased in fatty livers and induces inflammatory markers in an in vitro model of hepatic steatosis. Journal of Hepatology, 56(3), 647-655. https://doi.org/10.1016/j.jhep.2011.07.028

Berner, A. K., Brouwers, O., Pringle, R., Klaassen, I., Colhoun, L., McVicar, C., Brockbank, S., Curry, J. W., Miyata, T., Brownlee, M., Schlingemann, R. O., Schalkwijk, C., & Stitt, A. W. (2012). Protection against methylglyoxal-derived AGEs by regulation of glyoxalase 1 prevents retinal neuroglial and vasodegenerative pathology. Diabetologia, 55(3), 845-854. https://doi.org/10.1007/s00125-011-2393-0

Van Woudenbergh, G. J., Kuijsten, A., Van der Kallen, C. J., Van Greevenbroek, M. M., Stehouwer, C. D., Blaak, E. E., & Feskens, E. J. M. (2012). Comparison of fatty acid proportions in serum cholesteryl esters among people with different glucose tolerance status: The CoDAM study. Nutrition Metabolism and Cardiovascular Diseases, 22(2), 133-140. https://doi.org/10.1016/j.numecd.2010.05.008

Hustad, S., Eussen, S., Midttun, O., Ulvik, A., van de Kant, P. M., Morkrid, L., Gislefoss, R., & Ueland, P. M. (2012). Kinetic Modeling of Storage Effects on Biomarkers Related to B Vitamin Status and One-Carbon Metabolism. Clinical Chemistry, 58(2), 402-410. https://doi.org/10.1373/clinchem.2011.174490

Nin, J. W. M., Ferreira, I., Schalkwijk, C. G., Prins, M. H., Chaturvedi, N., Fuller, J. H., & Stehouwer, C. D. A. (2012). Serum high-mobility group box-1 levels are positively associated with micro- and macroalbuminuria but not with cardiovascular disease in type 1 diabetes: the EURODIAB Prospective Complications Study. European Journal of Endocrinology, 166(2), 325-332. https://doi.org/10.1530/EJE-11-0662

Bieghs, V., van Gorp, P. J., Wouters, K., Hendrikx, T., Gijbels, M. J., van Bilsen, M., de Bakker, J., Binder, C. J., Lutjohann, D., Staels, B., Hofker, M. H., & Sverdlov, R. (2012). LDL receptor knock-out mice are a physiological model particularly vulnerable to study the onset of inflammation in non-alcoholic fatty liver disease. PLOS ONE, 7(1), Article e30668. https://doi.org/10.1371/journal.pone.0030668

Croes, S., Koop, A. H., van Gils, S. A., & Neef, C. K. (2012). Efficacy, nephrotoxicity and ototoxicity of aminoglycosides, mathematically modelled for modelling-supported therapeutic drug monitoring. European Journal of Pharmaceutical Sciences, 45(1-2), 90-100. https://doi.org/10.1016/j.ejps.2011.10.022

van Onzenoort, H. A. W., Verberk, W. J., Kroon, A. A., Kessels, A. G. H., Neef, C., van der Kuy, P. H. M., & de Leeuw, P. W. (2012). Electronic monitoring of adherence, treatment of hypertension, and blood pressure control. American Journal of Hypertension, 25(1), 54-59. https://doi.org/10.1038/ajh.2011.153

Touwslager, R. N., Houben, A. J., Gielen, M. J. F., Zeegers, M. P. A., Stehouwer, C. D. A., Zimmermann, L. J. I., Kessels, A. G., Gerver, W. J. M., Blanco, C. E., & Mulder, A. L. M. (2012). Endothelial vasodilatation in newborns is related to body size and maternal hypertension.Journal of Hypertension, 30(1), 124-131. https://doi.org/10.1097/HJH.0b013e32834d75c6

van Greevenbroek, M. M. J., Jacobs, M., van der Kallen, C. J. H., Blaak, E. E., Jansen, E., Schalkwijk, C. G., Feskens, E. J. M., & Stehouwer, C. D. A. (2012). Human plasma complement C3 is independently associated with coronary heart disease, but only in heavy smokers (the CODAM study). International Journal of Cardiology, 154(2), 158-162. https://doi.org/10.1016/j.ijcard.2010.09.017

Touwslager, R. N. H., Gerver, W. J. M., Tan, F. E. S., Gielen, M., Zeegers, M. P., Zimmermann, L. J., Houben, A. J. H. M., Blanco, C. E., Stehouwer, C. D. A., & Mulder, A. L. M. (2012). Influence of Growth During Infancy on Endothelium-Dependent Vasodilatation at the Age of 6 Months. Hypertension, 60(5), 1294-1300. https://doi.org/10.1161/HYPERTENSIONAHA.112.199125

Scheijen, J. L. J. M., Hanssen, N. M., van de Waarenburg, M. P., Jonkers, D. M. A. E., Stehouwer, C. D. A., & Schalkwijk, C. G. (2012). L(+) and d(-) lactate are increased in plasma and urine samples of type 2 diabetes as measured by a simultaneous quantification of l(+) and d(-) lactate by reversed-phase liquid chromatography tandem mass spectrometry. Experimental Diabetes Research, 2012, Article 234812. https://doi.org/10.1155/2012/234812

van Bussel, B. C. T., Henry, R. M., Schalkwijk, C. G., Dekker, J. M., Nijpels, G., & Stehouwer, C. D. A. (2012). Low-grade inflammation, but not endothelial dysfunction, is associated with greater carotid stiffness in the elderly: the Hoorn Study. Journal of Hypertension, 30(4), 744-752. https://doi.org/10.1097/HJH.0b013e328350a487

Schiefer, M., Aquarius, M., Leffers, P., Stassen, P., van Deursen, C., Oostenbrug, L., Jansen, L., Masclee, A., & Keulemans, Y. C. (2012). Predictive validity of the Glasgow Blatchford Bleeding Score in an unselected emergency department population in continental Europe. European Journal of Gastroenterology & Hepatology, 24(4), 382-387. https://doi.org/10.1097/MEG.0b013e3283505965

Rouhl, R. P. W., Mertens, A. E. C. S., van Oostenbrugge, R. J., Damoiseaux, J. G. M. C., Debrus-Palmans, L. L., Henskens, L. H. G., Kroon, A. A., de Leeuw, P. W., Lodder, J., & Tervaert, J. W. C. (2012). Angiogenic T-Cells and Putative Endothelial Progenitor Cells in Hypertension-Related Cerebral Small Vessel Disease. Stroke, 43(1), 256-U509. https://doi.org/10.1161/STROKEAHA.111.632208

Krijnen, P. A. J., Hahn, N. E., Kholova, I., Baylan, U., Sipkens, J. A., van Alphen, F. P., Vonk, A. B. A., Simsek, S., Meischl, C., Schalkwijk, C. G., van Buul, J. D., van Hinsbergh, V. W. M., & Niessen, H. W. M. (2012). Loss of DPP4 activity is related to a prothrombogenic status of endothelial cells: implications for the coronary microvasculature of myocardial infarction patients. Basic Research in Cardiology, 107(1), 233. https://doi.org/10.1007/s00395-011-0233-5

Wlazlo, N., van Greevenbroek, M. M. J., Ferreira, I., Bravenboer, B., & Stehouwer, C. D. A. (2012). The diagnosis of non-alcoholic fatty liver disease. Alimentary Pharmacology & Therapeutics, 35(1), 204-205. https://doi.org/10.1111/j.1365-2036.2011.04909.x

Hoppe, U. C., Brandt, M.-C., Wachter, R., Beige, J., Rump, L. C., Kroon, A. A., Cates, A. W., Lovett, E. G., & Haller, H. (2012). Minimally invasive system for baroreflex activation therapy chronically lowers blood pressure with pacemaker-like safety profile: results from the Barostim neo trial. Journal of the American Society of Hypertension, 6(4), 270-276. https://doi.org/10.1016/j.jash.2012.04.004

le Poole, C. Y., van Ittersum, F. J., Valentijn, R. M., Teerlink, T., Lindholm, B., Ter Wee, P. M., & Schalkwijk, C. G. (2012). "NEPP" PERITONEAL DIALYSIS REGIMEN HAS BENEFICIAL EFFECTS ON PLASMA CEL AND 3-DG, BUT NOT PENTOSIDINE, CML, AND MGO. Peritoneal Dialysis International, 32(1), 45-54. https://doi.org/10.3747/pdi.2010.00101

Touwslager, R. N., Gielen, M. J. F., Mulder, A. L. M., Gerver, W. J. M., Zimmermann, L. J. I., Fowler, T., Houben, A. J., Stehouwer, C. D. A., Derom, C., Vlietinck, R., Loos, R. J., & Zeegers, M. P. A. (2011). Changes in genetic and environmental effects on growth during infancy. American Journal of Clinical Nutrition, 94(6), 1568-1574. https://doi.org/10.3945/ajcn.111.012757

van de Laar, R. J. J., Stehouwer, C. D. A., Boreham, C. A., Murray, L. M., Schalkwijk, C. G., Prins, M. H., Twisk, J. W. R., & Ferreira, I. (2011). Continuing smoking between adolescence and young adulthood is associated with higher arterial stiffness in young adults: the Northern Ireland Young Hearts Project. Journal of Hypertension, 29(11), 2201-2209. https://doi.org/10.1097/HJH.0b013e32834b0ecf

Jonk, A. M., Houben, A. J., Schaper, N. C., de Leeuw, P. W., Serne, E. H., Smulders, Y. M., & Stehouwer, C. D. A. (2011). Obesity is associated with impaired endothelial function in the postprandial state.Microvascular Research, 82(3), 423-429. https://doi.org/10.1016/j.mvr.2011.08.006

van Onzenoort, H. A. W., Menger, F. E., Neef, C., Verberk, W. J., Kroon, A. A., de Leeuw, P. W., & van der Kuy, P.-H. M. (2011). Participation in a Clinical Trial Enhances Adherence and Persistence to Treatment A Retrospective Cohort Study. Hypertension, 58(4), 573-578. https://doi.org/10.1161/HYPERTENSIONAHA.111.171074

Weijs, B., Blaauw, Y., Rennenberg, R. J. M. W., Schurgers, L. J., Timmermans, C. C. M. M., Pison, L., Nieuwlaat, R., Hofstra, L., Kroon, A. A., Wildberger, J., & Crijns, H. J. G. M. (2011). Patients using vitamin K antagonists show increased levels of coronary calcification: an observational study in low-risk atrial fibrillation patients. European Heart Journal, 32(20), 2555-2562. https://doi.org/10.1093/eurheartj/ehr226

Campbell, D. J., Somaratne, J. B., Jenkins, A. J., Prior, D. L., Yii, M., Kenny, J. F., Newcomb, A. E., Schalkwijk, C. G., Black, M. J., & Kelly, D. J. (2011). Impact of type 2 diabetes and the metabolic syndrome on myocardial structure and microvasculature of men with coronary artery disease. Cardiovascular Diabetology, 10, 14. https://doi.org/10.1186/1475-2840-10-80

Falcao-Pires, I., Hamdani, N., Borbely, A., Gavina, C., Schalkwijk, C. G., van der Velden, J., van Heerebeek, L., Stienen, G. J. M., Niessen, H. W. M., Leite-Moreira, A. F., & Paulus, W. J. (2011). Diabetes Mellitus Worsens Diastolic Left Ventricular Dysfunction in Aortic Stenosis Through Altered Myocardial Structure and Cardiomyocyte Stiffness. Circulation, 124(10), 1151-1159. https://doi.org/10.1161/CIRCULATIONAHA.111.025270

Cudejko, C., Wouters, K., Fuentes, L., Hannou, S. A., Paquet, C., Bantubungi, K., Bouchaert, E., Vanhoutte, J., Fleury, S., Remy, P., Tailleux, A., Chinetti-Gbaguidi, G., Dombrowicz, D., Staels, B., & Paumelle, R. (2011). p16INK4a deficiency promotes IL-4-induced polarization and inhibits proinflammatory signaling in macrophages. Blood, 118(9), 2556-66. https://doi.org/10.1182/blood-2010-10-313106

Maitland-van der Zee, A.-H., van Wieren-de Wijer, D. B. M. A., de Boer, A., Kroon, A. A., de Leeuw, P. W., Schiffers, P., Janssen, R. G. J. H., Psaty, B. M., Duijn, C. M. V., Stricker, B. H. C., & Klungel, O. H. (2011). Genetic variation in the renin-angiotensin system, use of renin-angiotensin system inhibitors and the risk of myocardial infarction. Journal of the Renin-angiotensin-aldosterone System, 12(3), 208-214. https://doi.org/10.1177/1470320310391834

van Tienen, F. H. J., van der Kallen, C. J. H., Lindsey, P. J., Wanders, R. J., van Greevenbroek, M. M. J., & Smeets, H. J. M. (2011). Preadipocytes of type 2 diabetes subjects display an intrinsic gene expression profile of decreased differentiation capacity. International Journal of Obesity, 35(9), 1154-1164. https://doi.org/10.1038/ijo.2010.275

Bisognano, J. D., Bakris, G., Nadim, M. K., Munoz Sanchez, J. L., Kroon, A. A., Schafer, J., de Leeuw, P. W., & Sica, D. A. (2011). Baroreflex Activation Therapy Lowers Blood Pressure in Patients With Resistant Hypertension Results From the Double-Blind, Randomized, Placebo-Controlled Rheos Pivotal Trial. Journal of the American College of Cardiology, 58(7), 765-773. https://doi.org/10.1016/j.jacc.2011.06.008

Croes, S., Stobberingh, E. E., Stevens, K. N. J., Knetsch, M. L. W., & Koole, L. H. (2011). Antimicrobial and Anti-Thrombogenic Features Combined in Hydrophilic Surface Coatings for Skin-Penetrating Catheters. Synergy of Co-embedded Silver Particles and Heparin. ACS Applied Materials & Interfaces, 3(7), 2543-2550. https://doi.org/10.1021/am200408f

Breyer, M. K., Rutten, E. P., Vernooy, J. H. J., Spruit, M. A., Dentener, M. A., van der Kallen, C. J., van Greevenbroek, M. M., & Wouters, E. F. M. (2011). Gender differences in the adipose secretome system in chronic obstructive pulmonary disease (COPD): A pivotal role of leptin. Respiratory Medicine, 105(7), 1046-1053. https://doi.org/10.1016/j.rmed.2011.02.001

Lalloyer, F., Wouters, K., Baron, M., Caron, S., Vallez, E., Vanhoutte, J., Bauge, E., Sverdlov, R., Hofker, M., Staels, B., & Tailleux, A. (2011). Peroxisome proliferator-activated receptor-alpha gene level differently affects lipid metabolism and inflammation in apolipoprotein E2 knock-in mice. Arteriosclerosis Thrombosis and Vascular Biology, 31(7), 1573-1579. https://doi.org/10.1161/ATVBAHA.110.220525

Jacobs, M., van Greevenbroek, M. M. J., van der Kallen, C. J. H., Ferreira, I., Feskens, E. J., Jansen, E. H., Schalkwijk, C. G., & Stehouwer, C. D. (2011). The association between the metabolic syndrome and alanine amino transferase is mediated by insulin resistance via related metabolic intermediates (the Cohort on Diabetes and Atherosclerosis Maastricht [CODAM] study).Metabolism-Clinical and Experimental, 60(7), 969-975. https://doi.org/10.1016/j.metabol.2010.09.006

van den Born, B. J. H., Beutler, J. J., Gaillard, C. A. J. M., de Gooijer, A., van den Meiracker, A. H., & Kroon, A. A. (2011). Dutch guideline for the management of hypertensive crisis-2010 revision. Netherlands Journal of Medicine, 69(5), 248-255.

Jonk, A. M., Houben, A. J., Schaper, N. C., de Leeuw, P., Serne, E. H., Smulders, Y. M., & Stehouwer, C. D. A. (2011). Meal-related increases in microvascular vasomotion are impaired in obese individuals: a potential mechanism in the pathogenesis of obesity-related insulin resistance. Diabetes Care, 34 Suppl 2(SUPPL. 2), S342-S348. https://doi.org/10.2337/dc11-s240

van Greevenbroek, M. M. J., Jacobs, M., van der Kallen, C. J. H., Vermeulen, V. M., Jansen, E. H., Schalkwijk, C. G., Ferreira, I., Feskens, E. J., & Stehouwer, C. D. A. (2011). The cross-sectional association between insulin resistance and circulating complement C3 is partly explained by plasma alanine aminotransferase, independent of central obesity and general inflammation (the CODAM study).European Journal of Clinical Investigation, 41(4), 372-379. https://doi.org/10.1111/j.1365-2362.2010.02418.x

Engelen, L., Lund, S. S., Ferreira, I., Tarnow, L., Parving, H.-H., Gram, J., Winther, K., Pedersen, O., Teerlink, T., Barto, R., Stehouwer, C. D. A., Vaag, A. A., & Schalkwijk, C. G. (2011). Improved glycemic control induced by both metformin and repaglinide is associated with a reduction in blood levels of 3-deoxyglucosone in nonobese patients with type 2 diabetes. European Journal of Endocrinology, 164(3), 371-379. https://doi.org/10.1530/EJE-10-0851