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Wintjens, A. G. W. E., Fransen, P.-P. K. H., Lenaerts, K., Liu, H., van Almen, G. C., Gijbels, M. J., Janssen, B. J. A., de Hingh, I. H. J. T., Dankers, P. Y. W., Van Der Speeten, K., Bouvy, N. D., & Marchal, W. (2025). The pharmacokinetic profile of mitomycin C released from an injectable supramolecular hydrogel in a rodent model. Journal of controlled release : official journal of the Controlled Release Society, 383, Article 113763. https://doi.org/10.1016/j.jconrel.2025.113763

Van der Taelen, L., Briones, A. M., Unger, T., Staals, J., van Oostenbrugge, R. J., & Foulquier, S. (2025). Circulating immune cells in cerebral small vessel disease: a systematic review. Biogerontology, 26(3), Article 101. https://doi.org/10.1007/s10522-025-10250-x

Lambrichts, S. M. P., van Oostenbrugge, R. J., & Foulquier, S. (2025). TRPV4 in Cerebral Small Vessel Disease: A key interacting partner. Vascular Pharmacology, 159, Article 107492. https://doi.org/10.1016/j.vph.2025.107492

Pinckaers, N. E. T., Blankesteijn, W. M., Mircheva, A., Punt, A., Opperhuizen, A., van Schooten, F.-J., & Vrolijk, M. (2025). Quantitative in vitro-to-in vivo extrapolation of human adrenergic and trace amine-associated receptor 1 potencies of pre-workout supplement ingredients using physiologically based kinetic modelling-based reverse dosimetry. Archives of Toxicology, 99(5), 1999-2021. https://doi.org/10.1007/s00204-025-03992-7

Berends, E., Vangrieken, P., Amiri, N., van de Waarenburg, M. P. H., Scheijen, J. L. J. M., Hermes, D. J. H. P., Wouters, K., van Oostenbrugge, R. J., Schalkwijk, C. G., & Foulquier, S. (2025). Increased Levels of Circulating Methylglyoxal Have No Consequence for Cerebral Microvascular Integrity and Cognitive Function in Young Healthy Mice. Molecular Neurobiology, 62(4), 4190-4202. Article 101148. https://doi.org/10.1007/s12035-024-04552-3

Huang, Y., Chen, H., Chen, W., Chen, W., Zhong, Q., Pei, J., Zhang, M., & Haenen, G. R. M. M. (2025). Development and Application of Polyphenols in Food: A Comprehensive Review. Food Frontiers, 6(3), 1287-1302. https://doi.org/10.1002/fft2.533

Vangrieken, P., Scheijen, J. L. J. M., Schiffers, P. M. H., van de Waarenburg, M. P. H., Foulquier, S., & Schalkwijk, C. C. G. (2025). Modelling the effects of elevated methylglyoxal levels on vascular and metabolic complications. Scientific Reports, 15(1), Article 6025. https://doi.org/10.1038/s41598-025-90661-5

Donker, E. M., van Rosse, F., Janssen, B. J. A., Knol, W., Dumont, G., van Smeden, J., Atiqi, R., Hessel, M., Richir, M. C., van Agtmael, M. A., Kramers, C., Tichelaar, J., & Education committee of the Dutch Society for Clinical Pharmacology and Biopharmacy (2025). Students' perspective on the Dutch National Pharmacotherapy Assessment, a national survey study among final-year medical students. European Journal of Pharmacology, 989, Article 177266. https://doi.org/10.1016/j.ejphar.2025.177266

Donker, E. M., van Rosse, F., Janssen, B. J. A., Knol, W., Dumont, G., van Smeden, J., Atiqi, R., Hessel, M., Richir, M. C., van Agtmael, M. A., Kramers, C., Tichelaar, J., & Education committee of the Dutch Society for Clinical Pharmacology and Biopharmacy (2025). The impact of summative, formative or programmatic assessment on the Dutch National Pharmacotherapy Assessment: a retrospective multicentre study. European Journal of Pharmacology, 989, Article 177267. https://doi.org/10.1016/j.ejphar.2025.177267

Li, C., Wang, Y., Liang, J., Haenen, G. R. M. M., Chen, Y., Li, Z., Zhang, M., & Dubois, L. J. (2025). Exploring the Anticancer Potential of MonoHER (7-Mono-O-(β-Hydroxyethyl)-Rutoside): Mitochondrial-Dependent Apoptosis in HepG2 Cells. Current Issues in Molecular Biology, 47(1), Article 36. https://doi.org/10.3390/cimb47010036

Baker, M. B., Hazell, G., van Rijt, S., Blankesteijn, W. M., Welting, T., den Akker, G. V., & Bauer, J. (2025). Teaching Chemistry in the New Bachelor “Regenerative Medicine and Technology”. Croatica Chemica Acta, 98(2), 157-166. https://doi.org/10.5562/cca4185

Manukjan, N., Fulton, D., Ahmed, Z., Blankesteijn, W. M., & Foulquier, S. (2025). Vascular endothelial growth factor: a double-edged sword in the development of white matter lesions. Neural Regeneration Research, 20(1), 191-192. https://doi.org/10.4103/NRR.NRR-D-23-01843

Berends, E., Pencheva, M. G., van de Waarenburg, M. P. H., Scheijen, J. L. J. M., Hermes, D. J. H. P., Wouters, K., van Oostenbrugge, R. J., Foulquier, S., & Schalkwijk, C. G. (2024). Glyoxalase 1 overexpression improves neurovascular coupling and limits development of mild cognitive impairment in a mouse model of type 1 diabetes. Journal of Physiology, 602(22), 6209-6223. https://doi.org/10.1113/JP286723

Piët, J. D., Booth, A., Donker, E. M., de Ponti, F., Lunghi, C., Poluzzi, E., Janssen, B. J. A., Tun, S., Bekker, C., Dima, L., Costa, J., Jalving, M., Oude Munnink, T. H., van den Bemt, P. M. L. A., Labriffe, M., van Emden, T., van Waardenburg, V., Likic, R., Richir, M., ... Tichelaar, J. (2024). Environmentally sustainable prescribing: recommendations for EU pharmaceutical legislation. The Lancet. Planetary health, 8(10), e715-e716. https://doi.org/10.1016/S2542-5196(24)00230-4

Li, Z., Xu, L., Huang, D., Li, C., Haenen, G. R. M. M., & Zhang, M. (2024). NR0B2 Is a Key Factor for Gastric Diseases: A GEO Database Analysis Combined with Drug-Target Mendelian Randomization. Genes, 15(9), Article 1210. https://doi.org/10.3390/genes15091210

Vangrieken, P., Al-Nasiry, S., Remels, A. H. V., Schiffers, P. M. H., Janssen, E., Nass, S., Scheijen, J. L. J. M., Spaanderman, M. E. A., & Schalkwijk, C. G. (2024). Placental Methylglyoxal in Preeclampsia: Vascular and Biomarker Implications. Hypertension, 81(7), 1537-1549. https://doi.org/10.1161/HYPERTENSIONAHA.123.22633

Manukjan, N., Chau, S., Caiment, F., van Herwijnen, M., Smeets, H. J., Fulton, D., Ahmed, Z., Blankesteijn, W. M., & Foulquier, S. (2024). Wnt7a Decreases Brain Endothelial Barrier Function Via β-Catenin Activation. Molecular Neurobiology, 61(7), 4854-4867. https://doi.org/10.1007/s12035-023-03872-0

van der Laan, K. W. F., Reesink, K. D., Lambrichts, S., Bitsch, N. J. J. E., van der Taelen, L., Foulquier, S., Delhaas, T., Spronck, B., & Giudici, A. (2024). Effect of rapid cooling, frozen storage, and thawing on the passive viscoelastic properties and structure of the rat aorta. Journal of Biomechanics, 171, Article 112190. https://doi.org/10.1016/j.jbiomech.2024.112190

Pinckaers, N. E. T., Blankesteijn, W. M., Mircheva, A., Shi, X., Opperhuizen, A., van Schooten, F.-J., & Vrolijk, M. F. (2024). In Vitro Activation of Human Adrenergic Receptors and Trace Amine-Associated Receptor 1 by Phenethylamine Analogues Present in Food Supplements. Nutrients, 16(11), Article 1567. https://doi.org/10.3390/nu16111567

Donker, E. M., Osmani, H., Brinkman, D. J., van Rosse, F., Janssen, B., Knol, W., Dumont, G., Jorens, P. G., Dupont, A., Christiaens, T., van Smeden, J., de Waard-Siebinga, I., Peeters, L. E. J., Goorden, R., Hessel, M., Lissenberg-Witte, B. I., Richir, M. C., van Agtmael, M. A., Kramers, C., ... Education committee of the Dutch Society for Clinical Pharmacology and Biopharmacy (2023). The impact of a summative national prescribing assessment and curriculum type on the development of the prescribing competence of junior doctors. European Journal of Clinical Pharmacology, 79(12), 1613 - 1621. https://doi.org/10.1007/s00228-023-03567-4

Nelissen, E., Schepers, M., Ponsaerts, L., Foulquier, S., Bronckaers, A., Vanmierlo, T., Sandner, P., & Prickaerts, J. (2023). Soluble guanylyl cyclase: A novel target for the treatment of vascular cognitive impairment?Pharmacological Research, 197(1), Article 106970. https://doi.org/10.1016/j.phrs.2023.106970

Berends, E., van Oostenbrugge, R. J., Foulquier, S., & Schalkwijk, C. G. (2023). Methylglyoxal, a highly reactive dicarbonyl compound, as a threat for blood brain barrier integrity. Fluids and barriers of the CNS, 20(1), Article 75. https://doi.org/10.1186/s12987-023-00477-6

Giudici, A., van der Laan, K. W. F., van der Bruggen, M. M., Parikh, S., Berends, E., Foulquier, S., Delhaas, T., Reesink, K. D., & Spronck, B. (2023). Constituent-based quasi-linear viscoelasticity: a revised quasi-linear modelling framework to capture nonlinear viscoelasticity in arteries. Biomechanics and modeling in mechanobiology, 22(5), 1607–1623. https://doi.org/10.1007/s10237-023-01711-8

Xu, Y., Li, Z., Wang, Y., Li, C., Zhang, M., Chen, H., Chen, W., Zhong, Q., Pei, J., Chen, W., Haenen, G. R. M. M., & Moalin, M. (2023). Unraveling the Antioxidant Activity of 2R,3R-dihydroquercetin. International Journal of Molecular Sciences, 24(18), Article 14220. https://doi.org/10.3390/ijms241814220

Manukjan, N., Majcher, D., Leenders, P., Caiment, F., van Herwijnen, M., Smeets, H. J. J., Suidgeest, E., van der Weerd, L., Vanmierlo, T., Jansen, J. F. A., Backes, W. H. H., van Oostenbrugge, R. J. J., Staals, J., Fulton, D., Ahmed, Z., Blankesteijn, W. M., & Foulquier, S. (2023). Hypoxic oligodendrocyte precursor cell-derived VEGFA is associated with blood-brain barrier impairment. Acta neuropathologica communications, 11(1), Article 128. https://doi.org/10.1186/s40478-023-01627-5

Kerkhofs, D., Helgers, R., Hermes, D., Steinbusch, H. P. J., Van Essen, H., Leenders, P., Prickaerts, J., Staals, J., Biessen, E. A., Van Oostenbrugge, R. J., & Foulquier, S. (2023). Amlodipine limits microglia activation and cognitive dysfunction in aged hypertensive mice. Journal of Hypertension, 41(7), 1159-1167. https://doi.org/10.1097/HJH.0000000000003445

Colin, M., Delaitre, C., Foulquier, S., & Dupuis, F. (2023). The AT(1)/AT(2) Receptor Equilibrium Is a Cornerstone of the Regulation of the Renin Angiotensin System beyond the Cardiovascular System. Molecules, 28(14), Article 5481. https://doi.org/10.3390/molecules28145481

Haenen, G. R. M. M. (2023). Past, Present and Future of the Section "Molecular Toxicology". International Journal of Molecular Sciences, 24(7), Article 6667. https://doi.org/10.3390/ijms24076667

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Donker, E. M., Brinkman, D. J., van Rosse, F., Janssen, B., Knol, W., Dumont, G., Jorens, P. G., Dupont, A., Christiaens, T., van Smeden, J., de Waard-Siebinga, I., Peeters, L. E. J., Goorden, R., Hessel, M., Lissenberg-Witte, B., Richir, M., van Agtmael, M., Kramers, C., Tichelaar, J., & Education committee of the Dutch Society for Clinical Pharmacology and Biopharmacy (2022). Do we become better prescribers after graduation: A 1-year international follow-up study among junior doctors. British Journal of Clinical Pharmacology, 88(12), 5218-5226. https://doi.org/10.1111/bcp.15443

Douven, P., Franken, G., Debets, J., Joosten, E. A., Van Koeveringe, G. A., Melenhorst, J., & Breukink, S. O. (2022). Vaginal Distention Rodent Model for Fecal Incontinence: A Pilot Study on the Effect on Defecation Behavior. Journal of Coloproctology, 42(3), 217-222. https://doi.org/10.1055/s-0042-1750074

Pinckaers, N., Blankesteijn, M., Opperhuizen, A., Van Schooten, F. J., & Vrolijk, M. (2022). In vitro pharmacological characterization of phenethylamine and alkylamine analogues found in nutritional supplements at human adrenergic and trace amine-associated receptors. Toxicology Letters, 368, S280-S280. https://doi.org/10.1016/j.toxlet.2022.07.739

Kemps, H., Dessy, C., Dumas, L., Sonveaux, P., Alders, L., Van Broeckhoven, J., Font, L. P., Lambrichts, S., Foulquier, S., Hendrix, S., Brône, B., Lemmens, R., & Bronckaers, A. (2022). Extremely low frequency electromagnetic stimulation reduces ischemic stroke volume by improving cerebral collateral blood flow. Journal of Cerebral Blood Flow and Metabolism, 42(6), 979-996. Article 0271678X221084410. https://doi.org/10.1177/0271678X221084410

Neradova, A., Wasilewski, G., Prisco, S., Leenders, P., Caron, M., Welting, T., van Rietbergen, B., Kramann, R., Floege, J., Vervloet, M. G., & Schurgers, L. J. (2022). Combining phosphate binder therapy with vitamin K2 inhibits vascular calcification in an experimental animal model of kidney failure. Nephrology Dialysis Transplantation, 37(4), 652-662. https://doi.org/10.1093/ndt/gfab314

Li, Z., Zhang, M., Haenen, G. R. M. M., Vervoort, L., & Moalin, M. (2022). Flavonoids Seen through the Energy Perspective. International Journal of Molecular Sciences, 23(1), Article 187. https://doi.org/10.3390/ijms23010187

Segers, F. M. E., Ruder, A. V., Westra, M. M., Lammers, T., Dadfar, S. M., Roemhild, K., Lam, T. S., Eline Kooi, M., Cleutjens, K. B. J. M., Verheyen, F. K., Schurink, G. W. H., Haenen, G. R., van Berkel, T. J. C., Bot, I., Halvorsen, B., Sluimer, J. C., & Biessen, E. A. L. (2022). Magnetic resonance imaging contrast-enhancement with superparamagnetic iron oxide nanoparticles amplifies macrophage foam cell apoptosis in human and murine atherosclerosis. Cardiovascular Research, 118, 3346-3359. https://doi.org/10.1093/cvr/cvac032

Jedrzejczyk, M. A., Van den Bosch, S., Van Aelst, J., Van Aelst, K., Kouris, P. D., Moalin, M., Haenen, G. R. M. M., Boot, M. D., Hensen, E. J. M., Lagrain, B., Sels, B. F., & Bernaerts, K. V. (2021). Lignin-Based Additives for Improved Thermo-Oxidative Stability of Biolubricants. ACS Sustainable Chemistry & Engineering, 9(37), 12548-12559. https://doi.org/10.1021/acssuschemeng.1c02799

van Gorp, R. H., Baaten, C. C. F. M. J., Habibi, A., Jaminon, A. M. G., Peeters, F. E. C. M., Leenders, P., Crijns, H. J. G. M. C., Heemskerk, J. W. M., Reutelingsperger, C. P., Spronk, H. M., & Schurgers, L. J. (2021). Vitamin K antagonist use induces calcification and atherosclerotic plaque progression resulting in increased hypercoagulability. European heart journal open, 1(2), Article oeab017. https://doi.org/10.1093/ehjopen/oeab017

Laukkanen, L., Diniz, C. R. A. F., Foulquier, S., Prickaerts, J., Castren, E., & Casarotto, P. C. (2021). Facilitation of TRKB Activation by the Angiotensin II Receptor Type-2 (AT2R) Agonist C21. Pharmaceuticals, 14(8), Article 773. https://doi.org/10.3390/ph14080773

Vangrieken, P., Al-Nasiry, S., Bast, A., Leermakers, P. A., Tulen, C. B. M., Schiffers, P. M. H., van Schooten, F. J., & Remels, A. H. V. (2021). Placental Mitochondrial Abnormalities in Preeclampsia. Reproductive Sciences, 28(8), 2186-2199. https://doi.org/10.1007/s43032-021-00464-y

Franken, G., Douven, P., Debets, J., & Joosten, E. A. J. (2021). Conventional Dorsal Root Ganglion Stimulation in an Experimental Model of Painful Diabetic Peripheral Neuropathy: A Quantitative Immunocytochemical Analysis of Intracellular gamma-Aminobutyric Acid in Dorsal Root Ganglion Neurons. Neuromodulation, 24(4), 639-645. https://doi.org/10.1111/ner.13398

van Gorp, R. H., Dijkgraaf, I., Bröker, V., Bauwens, M., Leenders, P., Jennen, D., Dweck, M. R., Bucerius, J., Briedé, J. J., van Ryn, J., Brandenburg, V., Mottaghy, F., Spronk, H. M. H., Reutelingsperger, C. P., & Schurgers, L. J. (2021). Off-target effects of oral anticoagulants - vascular effects of vitamin K antagonist and non-vitamin K antagonist oral anticoagulant dabigatran etexilate. Journal of Thrombosis and Haemostasis, 19(5), 1348-1363. https://doi.org/10.1111/jth.15289

Gouweleeuw, L., Wajant, H., Maier, O., Eisel, U. L. M., Blankesteijn, W. M., & Schoemaker, R. G. (2021). Effects of selective TNFR1 inhibition or TNFR2 stimulation, compared to non-selective TNF inhibition, on (neuro)inflammation and behavior after myocardial infarction in male mice. Brain Behavior and Immunity, 93, 156-171. https://doi.org/10.1016/j.bbi.2021.01.001

Daskalopoulos, E. P., & Blankesteijn, W. M. (2021). Effect of Interventions in WNT Signaling on Healing of Cardiac Injury: A Systematic Review. Cells, 10(2), Article 207. https://doi.org/10.3390/cells10020207

Vangrieken, P., Al-Nasiry, S., Bast, A., Leermakers, P. A., Tulen, C. B. M., Janssen, G. M. J., Kaminski, I., Geomini, I., Lemmens, T., Schiffers, P. M. H., van Schooten, F. J., & Remels, A. H. V. (2021). Hypoxia-induced mitochondrial abnormalities in cells of the placenta. PLOS ONE, 16(1), Article e0245155. https://doi.org/10.1371/journal.pone.0245155

Vangrieken, P., Remels, A. H., Al-Nasiry, S., Bast, A., Janssen, G. M. J., von Rango, U., Vroomans, D., Pinckers, Y. C. W., van Schooten, F. J., & Schiffers, P. M. H. (2020). Placental hypoxia-induced alterations in vascular function, morphology, and endothelial barrier integrity. Hypertension Research, 43(12), 1361-1374. https://doi.org/10.1038/s41440-020-0528-8

Reinhold, S., Blankesteijn, W. M., & Foulquier, S. (2020). The Interplay of WNT and PPARγ Signaling in Vascular Calcification. Cells, 9(12), Article 2658. https://doi.org/10.3390/cells9122658

Mastenbroek, T. G., Karel, M. F. A., Nagy, M., Chayoua, W., Korsten, E. I. J., Coenen, D. M., Debets, J., Konings, J., Brouns, A. E., Leenders, P. J. A., van Essen, H., van Oerle, R., Heitmeier, S., Spronk, H. M., Kuijpers, M. J. E., & Cosemans, J. M. E. M. (2020). Vascular protective effect of aspirin and rivaroxaban upon endothelial denudation of the mouse carotid artery. Scientific Reports, 10(1), Article 19360. https://doi.org/10.1038/s41598-020-76377-8